Job Description

The Department of Physics and Astronomy at Clemson University invites applications for a Postdoctoral Fellow position in Biophysics under the mentorship of Assistant Professor Dr. Sheng Liu

This position focuses on the development of a high-resolution single-particle tracking system based on MINFLUX microscopy to study protein dynamics and interactions in live cells. The successful candidate will play a central role in advanced instrumentation development and interdisciplinary biophysics research.

Primary research responsibilities include:

• Design, construction, and optimization of a MINFLUX microscope
• Development of instrument control software
• Data acquisition, processing, and quantitative analysis
• Preparation of manuscripts and grant proposals

Additional responsibilities may include:

• Cell line generation and biological sample preparation
• Development of data analysis algorithms for single-molecule and super-resolution data

Appointment Details

• Anticipated start date: September 1, 2026 (negotiable)
• Initial appointment: One year
• Renewal: Potential renewal based on performance and availability of funding

About Us:

For more information about Clemson, please visit the website http://www.clemson.edu/

For more information about the department and its programs, please visit the website https://www.clemson.edu/science/academics/departments/physics/

For more information about Dr. Sheng Liu’s lab, please visit the website https://liulabclemson.github.io/labwebsite/

Qualifications

Required:

• PhD in Optics, Physics, Electrical and Computer Engineering, Biomedical Engineering, or a closely related field, awarded or expected by 2026

Preferred Experience:

• Optical system design and alignment
• Instrument control software development
• Electronic circuit design and FPGA programming
• Cell culture and biological sample preparation

Preferred Programming and Software Skills:

• Julia, Python, MATLAB, CUDA, LabVIEW
• Zemax, Inventor, SolidWorks
• KiCad, Vivado, or related tools

Application Instructions

Review of applications will begin immediately; however, the position will remain open until filled.

Applicants should submit the following items via Interfolio at:

https://apply.interfolio.com/186637

1. Cover letter describing research interests and past research experience
2. Curriculum vitae, including publication list
3. Names and contact information for three professional references

For more information, please contact Dr. Sheng Liu at shengl@clemson.edu

Equal Employment Opportunity Statement

Clemson University is an EEO/AA employer. Employment decisions are made without regard to characteristics protected by applicable law including disability and protected veteran status.