Job Description

Summary

The Center for Drug Discovery (https://www.bcm.edu/research/centers/drug-discovery) is a strategic research center established at Baylor College of Medicine (BCM) in Houston, Texas. The mission of the Center for Drug Discovery is to establish novel discovery technologies that enable rapid and cost-effective drug discovery within the academic community. The lab is seeking a highly skilled and motivated postdoc with expertise in medicinal chemistry and/or organic chemistry to join the Center for Drug Discovery's DNA encoded chemical library (DEL) team.

Baylor College of Medicine typically follows similar to the NIH stipulated stipend guidelines for Postdoctoral Associates.

Job Duties

• Plans, directs, and conducts research experiments.
• Evaluates and analyzes data.
• Develops research techniques and performs applications required for specific research projects.
• Conducts literature searches and summarizes information in an appropriate format for a particular study.
• Documents results of experiments and reports to principal investigators.
• Participates in early stage drug discovery efforts in collaboration with biological scientists throughout the academic community, with a goal of bringing new treatments to patients with unmet medical needs.
• Synthesizes medicinal chemistry compounds that the Center for Drug Discovery request in a timely and efficient manner.
• Designs and synthesizes DNA-encoded libraries, contributes to DEL-based lead discovery, and engages in cross-functional scientific discussions.
• Contributes to multidisciplinary lead-finding project teams by engaging in the following activities: design, screen, and synthesize DNA-encoded chemical libraries; perform compound resynthesis and medicinal chemistry, optimization.
• Uncovers and utilizes novel chemical reactions in water; and/or evaluates compounds for efficacy in vitro and/or in vivo.
• Performs other job-related duties as assigned.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• PhD in medicinal/organic chemistry or a related discipline.
• >4 years of hands-on laboratory experience in medicinal/organic chemistry/DEL and/or a related field and a track record of quality publications and/or patents in these areas.
• Experience with one or more of the following: DEL design and synthesis, performing innovative chemistry reactions and compound synthesis.