Job Description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Are you interested in developing novel reagents and workflows for next generation sequencing?
We are looking for a highly talented and motivated postdoctoral fellow (m/f/d) to join our team on
this mission.

The Chemistry Technologies department provides the full spectrum of chemical diagnostic reagents, ranging from small molecules to biooligomers and polymers. Leveraging modern synthetic and analytical methods we design and develop tailor-made molecules to find the right solutions for diagnostic questions and beyond. We work as a team, are driven by passion for science and commitment to continuous learning to stay at the forefront of research.

Our culture is defined by trust, transparency, and a strong collaborative spirit. We are looking for a proactive colleague who balances independent critical thinking with team spirit and the flexibility to collaborate across diverse departments and interdisciplinary teams.

Your tasks

• Design and synthesize complex oligonucleotide-conjugates by contemporary bioconjugation techniques and small molecular entities by chemical synthesis
• Establish DNA templated proximity reactions for initial testing of your new reagent classes
• Collaborate proactively with project partners from biology, analytics and the sequencing test development teams to gain a deep insight into the relationship of structural design and assay performance
• Independently plan, execute and analyze experiments to effectively advance the projects
• Present scientific progress through internal meetings and visit scientific conferences to ensure the state-of-the-art knowledge in the field of bioorganic synthesis, chemical biology and surface chemistry
• Be part of a highly motivated and cross-functional team

Your profile

• You hold a PhD in the field of (bio)organic chemistry, chemical biology or life science.
• You possess profound knowledge in the synthesis of oligonucleotide-conjugates, preferably in context of biomolecules (proteins, peptides, nucleic acids)
• You are well experienced in organic synthesis
• Hands-on experience in the field of DNA-templated reactions, proximity reactions and nucleic acid detection completes your profile.
• Your qualification should be clearly demonstrated by at least one first author paper published or accepted in a high impact journal.
• Excellent communication and interpersonal skills are your strength. You are sensitive to intercultural and interdisciplinary matters - working in a team comes natural to you.
• You are a proactive individual with passion and commitment to innovate healthcare through our Roche Diagnostics Postdoc Program.
• Excellent English skills are required, German is not mandatory.

When does it start?

This position will be filled with effect Septmber 2026 and is limited to 2 years.

Have we aroused your interest?

# If we are convinced, a virtual interview will take place
# If you also manage to convince us here, the last step is an interview and presentation in the
Penzberg area

Your application

Please submit your application by sending an updated CV (including publication list and
references) together with your latest certificates. Before sending your application, please note
that no further documents can be added subsequently.

We are looking forward to your application!

Your contact to us! With people. For people.

Do you need further support?

Please have a look at our FAQs, you will find them via https://careers.roche.com/global/en/faq

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.