University of Colorado Anschutz
Department: Physiology and Biophysics
Working Title: Postdoctoral Fellow
Position #00850568 – Requisition #40496
Nature of Work
The Fernández-Mariño lab is seeking to hire a postdoctoral fellow. The position will focus on university compliance, lab organization, and inventory, and has reserved time (approximately 50%) to contribute to other aspects of the lab’s research. These aspects include investigating the molecular mechanisms of membrane proteins using an integrative approach combining biochemistry, biophysics, and structural biology. The lab is looking for a creative and motivated scientist interested in understanding how changes in protein structure control biological function. The project will focus on the biochemical and structural characterization of voltage-gated ion channels and its regulation by nanoantibodies in disease signaling pathways.
The lab is located within the University of Colorado School of Medicine Department of Physiology & Biophysics and the Aurora/Denver Anschutz Medical campus. Postdoctoral fellows will benefit from a multidisciplinary, vibrant, open, and collegial department.The Fernández-Mariño lab provides rich opportunities to interact with other biophysics and physology laboratories within the department,also with an even larger collection of systems neuroscience laboratories studying the neural basis of sensory-motor behaviors.
Supervision Received
The Postdoctoral Fellow will be supervised by Dr. Ana Fernández-Mariño, Ph.D.
Examples of Work Performed
Perform experiments and tabulate and analyze research data
Oral communication of preliminary results at lab meetings
Oral and written communication of completed work at national or international meetings.
Create figures and write papers
Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions
Utilize a variety of laboratory techniques required for research projects
Independently and creatively identify laboratory solutions
Independently review, develop and implement new or modified laboratory techniques required for research projects
Provide laboratory science expertise and leadership in study design, study oversight, data management, data analysis and manuscript preparation to assist all levels of investigators, researchers and clinicians on new research activities across a wide range of disciplines
Work Location:
Onsite – this role is expected to work onsite and is located in Aurora, CO.
Why Join Us:
Why work for the University?
The University of Colorado offers a comprehensive benefits package. To see what benefits are available for Post-Doctoral Fellows, please visit:
Qualifications:
Minimum Requirements:
Applicants must meet minimum qualifications at the time of hire.
Minimum requirements must be identifiable from the CV/Resume
Ph.D. in biochemistry, structural biology, molecular biology, biophysics, neuroscience, or a related field
A record of first-author publications
Preferred Qualifications: (
Identifiable from the CV/Resume
Experience with any of the following:
Molecular Biology
Expression and purification of recombinant proteins
Membrane protein production and characterization
Protein engineering and biochemical assay development
Nanobody discovery, selection, characterization
Structural biology approaches (preferably cryo-EM)
Biophysical characterization of protein structure
Experience with membrane proteins and/or nanobody technologies is highly desirable. Expertise in structural biology would be a major advantage, but enthusiasm for learning new approaches and addressing challenging biological questions is equally valued.
Knowledge, Skills, and Abilities:
Advanced knowledge of laboratory techniques including safety procedures and techniques
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
Ability to interpret and master complex research protocol information
Knowledge on molecular biology
How to Apply:
For full consideration, please submit the following document(s):
1.A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
2.Curriculum vitae / Resume
3.Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address
Applications are accepted electronically ONLY at www.cu.edu/cu-careers
Questions should be directed to: ANA.FERNANDEZ-MARINO@CUANSCHUTZ.EDU
Screening of Applications Begins:
Applications will be accepted until finalists are identified, but preference will be given to complete applications received by August 31, 2026. Those who do not apply by this date may or may not be considered.
Anticipated Pay Range:
The starting salary range (or hiring range) for this position has been established as HIRING RANGE:
$63,480 - $67,000
The above salary range (or hiring range) represents the University’s good faith and reasonable estimate of the range of possible compensation at the time of posting. This position is not eligible for overtime compensation unless it is non-exempt.
Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
Total Compensation Calculator: http://www.cu.edu/node/153125
Equal Employment Opportunity Statement:
The University of Colorado (CU) is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.
ADA Statement:
The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@ucdenver.edu.
Background Check Statement:
The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.
Vaccination Statement:
CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in theoccupational health medical surveillance program
