
At Headlands Research, we are dedicated to enhancing clinical trial delivery within our communities. As a leading network of advanced clinical trial sites, we leverage cutting-edge technology and exceptional support services to broaden outreach and participation. Founded in 2018, our rapidly growing company currently operates 20+ sites across the US and Canada, with plans for further expansion.
📍 Location: San Juan, PR | 🏥 Site Name: CMR Center | 🕒 Full-Time | 🧪 Clinical Research
We’re seeking an experienced physician for our clinical research site located in San Juan, PR to serve as our Principal Investigator on clinical trials. The Principal Investigator is responsible for ensuring subject safety, protocol compliance, data integrity, and high-quality study execution in accordance with FDA regulations, ICH-GCP guidelines, sponsor requirements, and company standards.
This role is ideal for a physician who is interested in clinical research, passionate about improving patient access to innovative therapies, and helping expand research opportunities in the community. In addition to clinical and study oversight responsibilities, the Principal Investigator will support business development and community engagement efforts, including attending sponsor meetings, conducting physician outreach, attending community education events, engaging in media interviews, and others that help build awareness of clinical research.
Type: Regular Full-time Employee
Schedule: Mondays through Fridays, 8:00am - 5:00pm
Location: Onsite in San Juan, PR (no capabilities for remote or hybrid work)
Reports to: Site President
Benefits: Our benefits package for full-time employees includes health insurance (medical, dental, and vision), Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA), Paid Time Off (PTO), a variety of disability, accident, and life insurance options, as well as many more.
CMRC Headlands is a premier clinical research site conducting Phase II–IV clinical trials in collaboration with global pharmaceutical sponsors. We advance medical innovation while placing patient experience and operational excellence at the heart of our mission.
Diversity isn't just a checkbox for us—it's central to our mission. We're committed to advancing medical science by promoting diversity in every facet of clinical trial research. From our team composition to participant demographics, inclusivity is at the heart of everything we do.
Headlands Research will never ask a candidate for personal identifiable information (date of birth, social security number, driver’s license information, etc) via email or messenger tools, or for a financial deposit of any kind.
Headlands Research is an Equal Opportunity Employer. We do not discriminate on the basis of race, color, religion, age, sex, national origin, disability status, genetic information, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
Headlands Research is committed to providing access and reasonable accommodation in its employment for individuals with disabilities. To request disability accommodation in the application process, contact recruiting@headlandsresearch.com for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Headlands Research is a leading globally integrated site organization with a mission to improve patients’ lives by advancing innovative medical therapies. Headlands Research is comprised of the highest quality dedicated and embedded research centers across North America. Our investigators and sites have completed 5,000+ Phase I-IV trials to date in various TA areas including but not limited to Allergy, Cardiovascular, Dermatology, Emergency Medicine, Endocrinology, Family Medicine, Family Practice, Gastroenterology, Immunology, Infectious Disease Prophylaxis and Treatment, Internal Medicine, Nephrology, Neurology. Obstetrics and Gynecology (OB/GYN), Oncology, Ophthalmology, Orthopaedics, Otolaryngology (ENT), Pediatrics, Physical Medicine and Rehabilitation, Plastic Surgery, Preventive Medicine, Psychiatry, Urology and Vaccine.