Location: Vacaville, CA
This is a fully site‑based role. Working together in person supports close, real‑time collaboration and the technical precision needed to manufacture medicines to the highest quality and safety standards.
As Operational Excellence Manager, the incumbent leads efforts to deliver business results by working with teams to identify opportunities for improvement and taking accountability for rigorous execution and delivery. The Operational Excellence Manager oversees all OE activities at the Assets Level with the goal of enabling improved business results through the Daily Management System, Process Improvement, and Culture change. This role will partner with other Site Leadership Team and Asset Leadership Team members, to identify and drive positive change across the site and Assets, is an expert in identifying and implementing efficiency gains for projects at all levels of scope but in particular those which are multi dimensional, complex and critical to the site’s future. This includes but is not limited to assessing, scoping, standardizing and implementation.
What you will get:
The full-time base annual salary for this position is expected to range between $114,000 to $190,000. In addition, below you will find a comprehensive summary of the benefits package we offer:
What you will do :
What we are looking for:
About Lonza
At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.
Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.
Ready to shape the future of life sciences? Apply now.

Lonza is a pioneer and world leader in the CDMO industry, setting the pace with cutting-edge science, smart technology, and lean manufacturing. United by a common purpose, we turn our customers’ breakthrough innovations into viable therapies and manufacture the medicines of tomorrow.
Founded in Switzerland in 1897, our company is the first and original CDMO, and today we are more dynamic, agile and forward-focused than ever before. As one of the largest Western CDMOs, we bring together a global team of around 18,500 colleagues across five continents to deliver comprehensive, integrated solutions for our customers' complex needs.
For our customers and their patients, we bring quality, safety and reliability to bring life-enhancing and life-saving treatments to market at speed and at scale. For our colleagues, we strive to create a sense of belonging and inclusion where every person can thrive and bring their best.