Mavericks Wanted
When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on
In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.
Together we define white space, push boundaries, and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma. At BridgeBio, we value curiosity and experimentation—including the ethical & thoughtful use of AI to improve clarity, speed, and quality of work.
The Medical Director, Medical Affairs is a senior medical and scientific leadership role within Medical Affairs. This role is responsible for supporting the development and execution of the medical strategy for encaleret across clinical development programs, including autosomal dominant hypocalcemia type 1 (ADH1) and chronic hypoparathyroidism. The position is critical to advancing scientific engagement, evidence generation and dissemination, clinical development support, and lifecycle planning, and to preparing for United States launch and post marketing activities.
The Medical Director, Medical Affairs will serve as a key cross-functional partner, providing medical expertise and strategic leadership and partnership across Clinical Development, Regulatory, Commercial, Patient Advocacy, and Field Medical. This role will also represent BridgeBio externally with investigators, key opinion leaders (KOLs), patient organizations, and the broader scientific community.
Responsibilities
Support development and execution of the United States Medical Affairs strategy for encaleret in ADH1 and chronic hypoparathyroidism, and support Medical Affairs launch readiness and lifecycle planning, serving as an internal medical expert with scientific rigor and patient focused decision making
Lead integrated evidence generation planning and manage execution, including real world evidence generation, Phase 4 studies, registries, investigator initiated research support, and data integration activities
Lead an omnichannel Health Care Professional engagement strategy, integrating field and digital scientific exchange to gather insights and inform internal Medical Affairs programs
Build and sustain strategic relationships with key opinion leaders, investigators, and external stakeholders across endocrinology, nephrology, and related specialties, and lead advisory board and expert panel planning and execution
Partner with Clinical Development to support ongoing and planned clinical trials and contribute to scientific data disclosure and publication strategy development in collaboration with Scientific Communications
Provide medical leadership for peer to peer scientific exchange and external education programs, including scientific presentations and representation at scientific congresses, clinical meetings, and external forums
Serve as medical reviewer and approver for medical, commercial, and patient advocacy materials, and support patient finding initiatives and Field Medical strategy and training in partnership with cross functional stakeholders, ensuring compliance with applicable regulations and internal Medical Affairs policies
This position is hybrid/on-site role (San Francisco Bay Area)
Ability to travel up to ~40% for scientific meetings, advisory boards, and internal engagements
MD, DO, PharmD, PhD, or equivalent advanced scientific or clinical degree
5+ years of experience in Medical Affairs, Clinical Development, or related roles within the biopharmaceutical industry and/or academic medicine
Deep experience in endocrinology, rare diseases, or metabolic disorders strongly preferred
Demonstrated experience supporting late-stage development, launch preparation, and post-marketing medical activities
Strong scientific and clinical acumen with the ability to translate complex data into clear medical insights
Proven leadership and influence in cross-functional, matrixed environments
Excellent written and verbal communication skills
Strong understanding of regulatory and compliance requirements impacting Medical Affairs and field activities
Ability to work independently in a fast-paced, evolving organization
Strategic mindset with hands-on execution capability
You have demonstrated curiosity and adaptability in adopting AI-powered tools and technologies
#LI-LN1
At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.
Salary $220,000—$315,000 USD
As a global company, our comprehensive benefits may vary based on location. We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.
For USA based roles:
Financial & Rewards
Health & Well-Being
Skill Development & Career Paths:
BridgeBio finds, develops, and delivers breakthrough medicines for genetic diseases.
Millions worldwide are afflicted with genetic diseases, but small patient populations and industry reluctance to conduct early-stage development means that for many, treatments have not been forthcoming. We are committed to bridging this gap: between business case and scientific possibility, between patient and hope. BridgeBio creates a bridge from remarkable advancements in genetic science to patients with unmet needs via the entrepreneurial engine required to make life-changing medicines as rapidly as possible.
BridgeBio is committed to developing leaders as well as drugs. We are looking for individuals whose passion for creating life-changing medicines will inspire hands-on engagement and the dogged pursuit of novel solutions in the face of adversity.
