Job Description

At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.

We are hiring a Manufacturing Technician to join our growing team. This technician will support the assembly and build of our instrument platform. This role will focus on hands-on assembly of complex electromechanical systems including mechanical structures, fluidic systems, and internal electrical wiring within a complex instrument chassis. The Manufacturing Technician will play a critical role in executing prototype and pilot builds, supporting the transition from engineering development to scalable manufacturing. The ideal candidate is comfortable working in a fast-paced development environment and has experience assembling complex scientific or electromechanical instrumentation.

Responsibilities

• Perform hands-on assembly of complex electromechanical instruments

• Assemble mechanical chassis, structural components, and internal subassemblies

• Install and route fluidic systems, including tubing, manifolds, pumps, and valves

• Install and route electrical wiring and harnesses within instrument enclosures

• Integrate mechanical, electrical, and fluidic subsystems within the instrument chassis

• Execute engineering prototype builds, design verification builds, and pilot production builds

• Follow detailed work instructions and assembly procedures

• Verify correct installation and alignment of components during assembly

• Escalate assembly issues or deviations to engineering or operations teams

• Support troubleshooting and rework activities when required

• Complete required manufacturing documentation including Device History Records (DHR), build travelers, traceability records

• Record serial numbers and part traceability information

• Document deviations or observations during builds

• Provide redlines or suggested improvements to assembly instructions

• Provide feedback to engineering and operations teams regarding build challenges or assembly issues

• Document observations that may improve manufacturability or assembly efficiency

• Support continuous improvement of assembly processes during pilot builds

Requirements

• 3–7+ years of experience assembling complex electromechanical systems

• Experience working with mechanical assemblies, fluidics, and electrical wiring

• Experience working in prototype, NPI, or pilot manufacturing environments

• Preferred industries include:

  • Biotechnology / life sciences instrumentation

  • Medical devices

  • Analytical instrumentation

  • Semiconductor equipment

  • Aerospace instrumentation

Additional Requirements

• Strong attention to detail and assembly quality

• Ability to work independently after initial training

• Comfortable working in a fast-paced development environment

• Ability to identify and escalate build issues quickly

• Strong communication skills and ability to work cross-functionally with engineering teams