Engineering
Manager, Information Systems
Let’s do this. Let’s change the world.
The Manager, Information Systems will lead the Manufacturing Excellence product team responsible for delivering technology capabilities that improve business outcomes. This role will develop and lead a high-performing team, oversee technology delivery and operations, and ensure alignment with business strategy, enterprise standards, security, quality, and regulatory requirements.
The ideal candidate has strong leadership experience in technology-driven manufacturing or regulated environments, combined with knowledge of software delivery, product management, organizational transformation, and global team leadership.
Roles and Responsibilities
Lead and develop a diverse technology team within a global, matrixed organization.
Build a culture of collaboration, innovation, accountability, and continuous improvement.
Recruit, mentor, coach, and develop talent while promoting inclusive and effective ways of working.
Maintain strong relationships with business and technology leaders and communicate service roadmaps, delivery status, risks, and priorities.
Understand business processes, manufacturing workflows, and information needs and translate them into technology capabilities and measurable outcomes.
Develop and execute technology, product, and workforce plans aligned with organizational strategy.
Oversee the software-development lifecycle, including planning, design, delivery, deployment, operations, and support.
Work with product owners, service owners, architects, delivery teams, and vendors to ensure commitments are met.
Manage scope, schedules, risks, dependencies, resources, and escalations across technology initiatives.
Promote Agile, DevOps, automation, cloud, data, analytics, and AI capabilities where they provide business value.
Ensure technology solutions comply with enterprise architecture, cybersecurity, quality, privacy, and regulatory requirements.
Define and monitor performance metrics for delivery, reliability, service quality, adoption, and business outcomes.
Manage operating and product-team budgets, forecasts, vendor costs, and resource plans.
Participate in leadership, governance, and stakeholder meetings and facilitate cross-functional alignment.
Support change management and adoption of new technology products, processes, and ways of working.
Remain accountable for overall organizational compliance with applicable quality and regulatory requirements.
Basic Qualifications
Bachelor’s or Master’s degree with 8–12 years of experience in Business, Engineering, Information Technology, Computer Science, or a related field.
Must-Have Skills
Demonstrated experience leading technology initiatives, products, services, and teams.
Experience managing, coaching, and developing employees and matrixed teams.
Strong experience partnering with business leaders, product owners, and senior stakeholders.
Experience defining technology roadmaps, operating models, and delivery plans.
Strong understanding of software development, product management, Agile delivery, DevOps, and production operations.
Experience managing scope, budgets, risks, vendors, resources, and executive escalations.
Experience with technology governance, cybersecurity, quality, compliance, and risk management.
Experience in pharmaceutical, biotechnology, manufacturing, life sciences, or another regulated industry.
Strong business acumen, analytical thinking, decision-making, communication, and stakeholder-management skills.
Experience applying methodologies such as Agile, SAFe, Kanban, ITIL, or comparable frameworks.
Ability to manage multiple priorities and work effectively with global and virtual teams.
Good-to-Have Skills
Leadership experience within a pharmaceutical, biotechnology, manufacturing, or technology organization.
Experience leading software, cloud, data, analytics, automation, or AI-enabled product teams.
Broad knowledge of enterprise applications, architecture, infrastructure, data, integration, cybersecurity, and cloud platforms.
Experience managing strategic vendors, consulting firms, or managed-service providers.
Understanding of manufacturing systems, enterprise data platforms, and regulated computerized systems.
Experience with organizational transformation, change management, and product operating models.
Preferred Certifications
ITIL certification — preferred.
Agile or Scaled Agile Framework certification — preferred.
Product, project, program, cloud, or change-management certification — preferred.
Soft Skills
Excellent leadership, coaching, and team-management skills.
Strong transformation and change-management capabilities.
Exceptional communication, collaboration, negotiation, and presentation skills.
High degree of initiative, ownership, and accountability.
Ability to influence decisions and build trusted partnerships.
Strong analytical, problem-solving, and decision-making skills.
Ability to work effectively in a fast-paced, global, and matrixed environment.

Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier, fuller and longer. We helped establish the biotechnology industry, and we remain on the cutting-edge of innovation, using technology and human genetic data to push beyond what’s known today. Our investment in research and development has yielded a robust pipeline that builds on our existing portfolio of medicines to treat cancer, heart disease, osteoporosis, inflammatory diseases and rare diseases.
Amgen is one of 30 companies comprising the Dow Jones Industrial Average®, and part of the Nasdaq-100 Index®. In 2024, Amgen was named one of the “World’s Most Innovative Companies” by Fast Company and one of “America’s Best Large Employers” by Forbes.
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