The LEUKINE® Melanoma Program Team Leader (PTL) is the end-to-end business owner responsible for launch readiness of LEUKINE® in metastatic melanoma, starting with a focus on supply chain and regulatory readiness. The PTL will be accountable for the product’s performance across the full lifecycle, from late-stage development and registration through launch and commercialization to lifecycle expansion and supply continuity. A matrixed leader, the PTL is responsible for closely aligning with functional leaders to ensure program objectives are met.

This role carries full P&L responsibility and operates as the program’s general manager, integrating strategy and execution across CMC/Supply Chain, Clinical Development, Regulatory, Market Access, Medical Affairs, and Commercial functions.

PRIMARY RESPONSIBILITIES

Enterprise Accountability & P&L Ownership

• Owns full P&L including revenue, gross-to-net, operating expenses, and profitability with an initial focus on launch investment prioritization and management
• Leads integrated launch planning across all elements of the supply chain, regulatory, development, medical affairs and commercial defining clear deliverables and accountability
• Plans and executes on the most optimal launch that maximizes market uptake, patient adoption/convenience, guideline adoption as well as generation of value for PTx
• Drives forecasting, scenario planning, and risk management
• Authors key product development plans with clear goals, timelines, go/no-go decision points and target product profiles for clarity across the organization
• Oversees execution of plan deliverables and implements subteams as needed
• Chairs cross-functional melanoma program team and ensures alignment across functions and key interdependencies
• Presents regular updates to Executive Leadership Team
• Develops and executes communication plan (including publications, presentations, and press relations).

Supply Chain Readiness

• Ensures supply readiness and lifecycle supply reliability for melanoma launch
• Ensures clear regulatory strategies to support new manufacturing process and new presentation at launch in US, EU, Australia and other target markets
• Evaluates path to create a new sargramostim brand for melanoma (e.g. formulation, flat dosing, presentation) and relevant regulatory strategy
• Ensures clear presentation lifecycle strategy, including DoW funded autoinjector. Garners customer insight to guide presentation decisions.
• Manages capacity, inventory, and manufacturing risks
• Registration Strategy
• Defines approval strategy and labeling approach in US and ex-US as well as optimal launch sequence
• Aligns regulatory strategy with access and commercial needs and articulates plans to fill gaps
• Ensures on time submission of key regulatory filings per plan

Development

• Defines labeling strategy
• Identifies and articulates plan to fill registration gaps in key markets
• Prepares development plan to expand indications

Pre-Launch and Launch Readiness

• Shapes integrated pre-launch strategy and launch strategy as well as tactics in partnership with all key stakeholders; ensures aligned prioritization of cross-functional tactics to realize plan, including launch sequence
• Sets revenue targets and aligns incentives
• Defines global pricing strategy with Market Access team
• Ensures that all launch activities are designed and executed in full alignment with applicable US and international regulatory requirements

KEY SUCCESS METRICS

• Supply reliability
• Successful regulatory milestones
• Launch performance and uptake
• Novel launch strategies
• Revenue growth and P&L performance

PEOPLE LEADERSHIP

• Leads and develops PTx Partners - Builds and inspires a high-performing, inclusive team where people feel empowered to do their best work and grow continuously. Provides timely, honest performance feedback; recognizes and rewards high achievement; and addresses underperformance with clarity and care
• Sets clear direction - Establishes cross-functional program goals, performance targets, and metrics that align with organizational priorities and ensures the team has the capabilities and capacity to deliver on them.
• Plans resources strategically - Identifies and recommends the human, financial, and technical resources needed to meet near- and long-term commitments while building toward lasting excellence.
• Communicates consistently - Maintains regular, two-way dialogue with program team members to keep goals, priorities, and expectations clear and mutually understood.
• Models the PTx culture - Leads by example, embodying PTx's core values - a passion for patient care, a commitment to excellence, relentless curiosity, and deep respect for all people - and brings those values to life through a strong culture of quality, accountability, and continuous improvement.
• Upholds compliance - Coaches and holds the team accountable for meeting all regulatory, quality, safety, and cGMP requirements, ensuring every team member has the training, knowledge, and skills to perform their role with confidence and integrity.

KNOWLEDGE, SKILLS, ABILITIES

Required:

• Business & Financial Acumen - Strong analytical and financial instincts, with the ability to translate market insights into actionable business strategies. Highly organized, with a proven ability to prioritize effectively, manage budgets, and deliver results on time; grounded in the principles of operational excellence.
• Strategic & Critical Thinking - A results-oriented, innovative thinker who brings strong problem-solving skills and sound judgment to complex challenges. Thrives in fast-paced environments and consistently moves teams forward with purpose and clarity.
• Communication & Influence - Exceptional communicator including written, verbal, and in presentation with the ability to engage, persuade, and align audiences at all levels of the organization. Runs effective meetings and fosters open, productive dialogue.
• Interpersonal Effectiveness - Brings a bias toward action, a consistently constructive outlook, and genuine comfort working across diverse teams and functions. Gives and receives feedback openly, adapts readily to change, and approaches unexpected challenges with composure.
• Regulatory Navigation - Adept at operating within complex regulatory environments, ensuring adherence to applicable laws and regulations while managing multiple priorities and projects simultaneously.
• Technical Proficiency - Strong Microsoft Office skills (Word, Excel, PowerPoint, Outlook) and quick to adopt new tools and applications as business needs evolve.

EXPERIENCE & EDUCATION

Required:

• Bachelor’s Degree
• 15+ years of progressively responsible experience in leadership or management consulting roles within biopharma industry primarily in team leadership, portfolio or program management (Master’s degree or equivalent in related field may substitute for 3 years of professional experience; terminal degree may substitute for 5 years of professional experience.)

Preferred:

• Advanced professional degree in life sciences (Ph.D., M.D., Pharm.D., MBA)

PTx is committed to the principles of pay equity and providing competitive compensation for all of our Partners. The current pay range for this position is $200,000 - $280,000: Offers are made within the base pay range applicable at the time. Your salary will vary depending on several factors including your qualifications and experience.

In addition to medical, dental, vision, FSA/DCA, HRA, disability, and life insurance coverage, all full-time, regular Partners enjoy a casual, and Hybrid or Remote workplace program for many roles. We offer a terrific compensation/benefits/perks package which includes an annual cash bonuses, 401k matching, free parking, Seattle-area ORCA pass, tuition assistance, plus rewards for achievement and contribution. To support a healthy work-life balance we also provide a gym subsidy, wellness participation programs, and a generous vacation, sick, and holiday paid time off program in addition to a paid shutdown between the Christmas and New Year’s holidays.

Partner Therapeutics is an Equal Opportunity Employer and does not discriminate on the basis of race, color, religion, sex, age, national origin, veteran status, marital status, sexual orientation, gender identity, disability or any other category prohibited by local, state, or federal law. This policy applies to all aspects of employment, including recruitment, placement, promotion, transfer, demotion, compensation, benefits, social and recreational activities, and termination.