
Over the last eight years, OpenEye Scientific has developed the field’s most advanced large-scale compute platform, Orion, built on Amazon Web Services. In this position, you will be working at the cutting edge of cloud computing, C++/Python development, and advanced MD simulation techniques. Your work will have the potential to make a major impact in drug discovery, and will be available to many pharmaceutical and biotech companies.
Scientists around the world use Orion for early-stage drug discovery and design in the pursuit of improving human health. Orion combines the power of advanced HPC, computational methods, and in-browser 3D visualization & modeling to solve problems in drug discovery & design. Our innovative solutions enable customers to routinely model billions of compounds in-silico. Orion enables our customers to interactively explore chemical space, evaluate designs and gain scientific understanding.
As a Back-End Engineer, you’ll work with designers, scientists, and software engineers to enhance & extend Orion's capabilities -- architecting and optimizing the high-performance compute and storage systems that drive groundbreaking scientific discoveries. You'll be part of a team building cutting edge features, as well as helping to modernize existing software.
Qualifications & Experience:
Interpersonal skills required:
OpenEye, Cadence Molecular Sciences is passionate about science and about taking care of team members, with leaders supporting your development and recognizing your contributions by providing an unmatched total compensation package in a collaborative, caring, energetic and fun work environment.

OpenEye, Cadence Molecular Sciences is an industry leader in computational molecular design based on decades of delivering rapid, robust, and scalable software, toolkits, and technology and design services across the drug discovery process. Our scientific approach has focused on visualizing and analyzing the shape and electrostatics of molecular 3D structures to inform and guide the advancement of pharmaceuticals and biotechnology.
OpenEye integrated its applications and toolkits into Orion, the only cloud-native, fully integrated molecular design platform. Combining unlimited computation and storage with powerful tools for data sharing, visualization and analysis in an open development platform, Orion offers unprecedented capabilities for drug discovery and optimization.
Founded in 1997, OpenEye was acquired by Cadence Design Systems (NASDAQ: CDNS) in August 2022. OpenEye is headquartered in Santa Fe, New Mexico, with offices in Boston, Massachusetts; Cologne, Germany; and Tokyo, Japan.