BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 10,000 colleagues spans five continents, with administrative offices in Basel, Beijing, and Cambridge, U.S. To learn more about BeOne, please visit www.beonemedicines.com and follow us on LinkedIn and X (formerly known as Twitter).
BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.
BeOne Medicines is seeking an innovative and driven Research Scientist to contribute to the development of our next-generation iPSC-derived cell therapy pipeline across oncology and immunology & inflammation (I&I) indications. The successful candidate will bring strong scientific judgment, hands-on research experience, and the ability to independently drive complex research activities from concept through execution.
In this role, you will apply expertise in areas such as iPSC biology, cell engineering, and immunological functional characterization to advance therapeutic programs. You will work closely with cross-functional teams to translate disease-specific therapeutic goals into actionable R&D plans, troubleshoot complex biological and technical challenges, and drive projects toward key milestones. Depending on experience and demonstrated capabilities, the role may provide opportunities to take on increasing project ownership and scientific leadership responsibilities.
Main Roles & Responsibilities
a. Conceptualize, design, and optimize robust strategies for iPSC differentiation and lineage assessment.
b. Translate high-level therapeutic objectives into rigorous, hypothesis-driven experimental roadmaps aligned with corporate pipeline milestones.
a. Drive project execution, including experimental planning, timeline management, data analysis, and coordination across multiple workstreams.
b.Collaborate effectively with cross-functional teams to ensure alignment of scientific objectives, priorities, and deliverables.
c. Synthesize complex datasets into clear, actionable presentations and technical reports for internal leadership, cross-functional teams, and external stakeholders.
a. Lead the design, optimization, and execution of comprehensive in vitro assays, including high-parameter multi-color flow cytometry, immune effector cytotoxicity, co-culture killing assays, and multiplex cytokine profiling.
b. Drive deep phenotypic and functional characterization of iPSC-derived cell products to support product and process development.
c. Develop and optimize fit-for-purpose analytical approaches to address program-specific scientific questions.
a. Provide support for GxP cleanroom activities as needed based on project requirements.
Requirements & Technical Skills
o In-depth hands-on and theoretical expertise in cell therapy and immunotherapy principles.
o Proven capability in high-parameter flow cytometry, immunological functional assays (e.g., CAR-T or NK/T-cell cytotoxicity, intracellular cytokine staining, cytokine bead array), and primary/engineered immune cell co-cultures.
o With an understanding of GxP cleanroom operations, process development, or translational cell therapy manufacturing is highly advantageous.
o Track record of independent research design, high-impact problem solving, and scientific publications or patent filings.
o Strong project management skills with the ability to balance scientific rigor against aggressive corporate timelines.
Working Conditions & Accountability
What We Offer To Our Valued Employees
BeOne Global Competencies
When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.
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Effective March 17, 2025, The U.S. subsidiary of BeiGene, Ltd. has changed its name to BeOne Medicines USA, Inc. This change comes ahead of our anticipated global rebranding to BeOne Medicines Ltd. and redomiciliation to Switzerland, pending shareholder approval. The new name reflects our commitment to develop innovative medicines and partner with the global community to help as many patients with cancer as possible.
To learn more about BeOne Medicines, please follow our new LinkedIn profile @BeOne Medicines.
