Job Description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

At the intersection of science and innovation, pRED’s Pharmaceutical Sciences (PS) organization enables the discovery and development of safe and effective therapeutics at optimal doses in relevant populations with a vision to power translation, continuously improve the accuracy of our predictions and accelerate the development of tomorrow's medicines. By seamlessly integrating our three core pillars—Translational Safety, Translational Pharmacology, and Biomarkers—we drive End to End asset development across the entire value chain, from target assessment to on-market support. Our mission is to continuously improve predictive accuracy, optimize dosing strategies for the right patient populations, and accelerate the development of tomorrow's safe and effective therapeutics.

The Opportunity

Serving as a technical expert within the ADME chapter of Pharmaceutical Sciences (PS). The primary objective is to drive the discovery portfolio forward by providing high-quality, actionable in vitro bioanalytical data that informs drug candidate selection.

• Mass Spectrometry & HPLC Operation: Independently develop and validate robust bioanalytical methods using HPLC and triple quad (Sciex) or high-resolution (e.g. Orbitrap/Thermo) mass spectrometry.

• Multi-Modality Quantification: Lead the quantification and rigorous data analysis for a diverse portfolio including small molecules, peptides, and oligonucleotides.

• Digital Transformation: Design and implement workflow automation and digitalization initiatives to streamline laboratory data flow and experimental execution.

• Strategic Throughput Optimization: Continuously evaluate and optimize the BA strategy to specifically increase sample throughput and reduce manual data analysis time.

• Large Molecule Support: Provide technical expertise for the quantification of large molecules as required by the pRED discovery pipeline.

• Optimize BA strategy to increase throughput and automation of data analysis

• Cross-Functional Collaboration: Partner with the ADME team to interpret bioanalytical results and influence project progression.

• Roche Leadership Framework: Demonstrate a Creative Mindset and VACC (Visionary, Architect, Catalyst, Coach) principles in all interactions, even as an individual contributor.

Who You Are

• An MSc or PhD degree in bioanalysis, biochemistry or a related relevant discipline, paired with proven practical experience, ideally within an industrial setting.

• Take full ownership of the quality, accuracy, and timely delivery of in vitro bioanalytical data supporting discovery projects.

• Exercise authority to permanently optimize laboratory processes, ensuring they meet evolving quality and efficiency standards.

• Act as a primary technical point of contact for internal stakeholders, utilizing high-level communication and collaboration skills to align on project needs.

• Apply economic and entrepreneurial thinking to prioritize tasks and manage laboratory resources effectively within the ADME department

• Permanently optimizes processes in order to increase quality and efficiency standards.

At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.