Location: Santa Clara, CA (Onsite)
Employment Type: Initial 6-month 1099 Contract
Reports To: Sr. Director of HR
Compensation: $40–$60/hour
T45 Labs is a Silicon Valley-based medical device innovation company dedicated to transforming breakthrough ideas into technologies that improve patient care. We partner with visionary entrepreneurs, engineers, physicians, and scientists to build and scale companies developing next-generation cardiovascular technologies.
Our team thrives in a collaborative, fast-paced startup environment where initiative is valued, achievement is recognized, bureaucracy is minimal, and individual contributions have a visible impact. We’re builders by nature, energized by helping innovative companies grow and develop technologies that improve patients’ lives.
This is an initial 6-month 1099 contract with the potential, but not guaranteed, opportunity to become a regular employee.
As the HR Generalist, you will provide hands-on HR support across T45 Labs and its portfolio companies. You will administer the systems, documentation, employee processes, and day-to-day activities that keep HR operations accurate, responsive, and moving forward. Administer and improve core HR operations and HRIS processes, including employee data, reporting, system accuracy, personnel records, and document maintenance.
This is an opportunity to do more than administer HR processes. You’ll help build the operational foundation that enables innovative medical device companies to grow and succeed.
You’ll work alongside talented engineers, scientists, and business leaders who are passionate about developing technologies that improve patients’ lives. Your work will be visible, your ideas will be welcomed, and strong performance and meaningful contributions will be recognized.
If you’re energized by building, enjoy creating order from complexity, and want your work to make a difference, we’d love to hear from you.
Candidates must be permanently authorized to work in the United States without the need for current or future visa sponsorship. We are currently unable to sponsor employment visas or permanent residency (PERM) applications.
This is an onsite position in our Santa Clara, CA office and is open to candidates currently residing within a reasonable commute distance from our office, without the need for relocation within or outside of California. There is no relocation package.
This is an initial 6-month 1099 contract with the potential, but not guaranteed, opportunity to become a regular employee. The anticipated pay range is $40 - $60 per hour. Actual hourly rate will be determined based on experience, qualifications, and other job-related factors. T45 Labs is committed to fair and equitable pay practices.
T45 Labs is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Employment decisions are based on qualifications, merit, and business needs. We do not discriminate based on race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other protected characteristic.
We do not accept unsolicited resumes from staffing agencies or recruiters without a signed agreement in place. Any resumes submitted without such an agreement will be considered the property of T45 Labs and no fees will be paid if the candidate is hired. Agencies interested in submitting candidates may email careers@t45labs.com.

T45 Labs is a Silicon Valley-based medtech incubator and investment platform that builds acquisition-ready cardiovascular companies.
We reduce development risk by advancing differentiated technologies through critical clinical and regulatory milestones.
T45 Labs follows a best-follower strategy: entering validated markets, refining early concepts, and focusing on outcomes, ease of use, and cost efficiency.
Through T45 Fund-I and T45 Fund-II, we partner with physicians and entrepreneurs to build differentiated cardiovascular companies with clear paths to strategic acquisition and attractive investor returns.