Job Description

Who We Are

Our Commercial organization leads our global sales and marketing strategies around the world. Our integrated team continues to solidify BioMarin’s commercial presence in the United States and Europe and is rapidly growing in other regions, such as Latin America, the Middle East and Asia-Pacific.

The Head of Marketing U.S. Enzyme Therapy (ET) is a senior commercial leader responsible for defining and executing the U.S. marketing strategy across BioMarin’s ET portfolio, spanning marketed therapies and late-stage pipeline assets across multiple rare disease indications. This role is accountable for driving marketing strategy, customer engagement, and brand performance to support overall franchise growth. The Head of Marketing reports into and partners closely with the VP, Head of U.S. ET to deliver on the business unit priorities. As a key member of the U.S. ET Leadership Team, this individual operates as a peer to Sales, Clinical Coordinators, Market Access, and Medical Affairs, translating enterprise and portfolio strategy into integrated brand plans, launch strategies, and execution excellence, while ensuring alignment across cross-functional partners and global stakeholders. Key Responsibilities Marketing Strategy & Execution

• Leads the development and execution of integrated U.S. marketing strategies across in-line and pipeline assets.

• Translates franchise priorities into clear brand strategies, positioning, and tactical plans in alignment with cross-functional partners.

• Drives customer-centric engagement strategies across HCP, patient, and caregiver audiences using omnichannel approaches.

• Lead the implementation of the BioMarin digital transformation and embed a new agile approach and mindset across the US marketing teams and the wider US team.

• Accountable for marketing performance metrics.

Brand & Portfolio Leadership

• Oversees development of annual brand plans and Integrated Brand Strategies, ensuring alignment with U.S. franchise priorities and cross-functional input.

• Provides strategic recommendations to inform portfolio prioritization and resource allocation decisions in partnership with U.S. ET leadership.

• Partners with the VP, Head of U.S. ET and peer leaders to ensure coordinated execution across brands and functions.

• Manages marketing budgets and cost centers, ensuring disciplined investment aligned with agreed strategic priorities.

Pipeline Commercialization & Launch Excellence

• Leads commercialization planning for pipeline assets, in close partnership with cross-functional leaders, including

• Disease-state education

• Diagnostic and patient identification strategies

• Market conditioning and pre-launch readiness

• Oversees cross-functional launch planning and execution, ensuring alignment across Marketing, Sales, Market Access, and Medical.

• Provides U.S. commercial input into development and global strategy discussions, representing market and customer insights.

Cross-Functional Leadership

• Partners as a peer leader with Sales, Clinical Coordinators, Market Access, Medical Affairs, and Business Operations teams to co-develop and execute an integrated franchise strategy.

• Ensures marketing strategies are aligned with field execution, access dynamics, and medical engagement to deliver consistent customer and patient experience.

• Drives alignment and operational excellence across cross-functional brand teams, without direct authority over peer functions.

External Engagement & Patient Focus

• Builds and maintains relationships with key opinion leaders, advocacy organizations, and external stakeholders.

• Partners with patient advocacy groups (e.g., NPKUA, National MPS Society, BDSRA, LPA) to ensure patient-centric strategy development.

• Ensures marketing strategies reflect a deep understanding of the rare disease patient journey and unmet needs.

People & Organizational Leadership

• Leads and develops a high-performing marketing organization, including Brand Leads and extended team members.

• Fosters a culture of accountability, collaboration, and innovation.

• Builds capabilities in data-driven marketing, omnichannel, and launch excellence.

• Attracts, develops, and retains top talent.

Qualifications Experience

• 10+ years of progressive commercial experience in biotech/pharmaceuticals, including significant U.S. marketing leadership.

• Proven track record of developing and executing successful brand strategies across multiple products or indications.

• Experience leading product launches and pre-launch commercialization efforts, ideally in rare disease or specialty markets.

• Strong experience working in complex, cross-functional and matrixed environments.

• Rare disease experience strongly preferred; global experience a plus.

Capabilities

• Strong strategic thinking and execution skills, with the ability to translate strategy into action.

• Deep understanding of the U.S. healthcare and reimbursement landscape.

• Expertise in data-driven decision making, analytics, and omnichannel marketing.

• Ability to influence cross-functional stakeholders and drive alignment without direct authority.

• Proven ability to build and lead high-performing teams.

Education

• Bachelor’s degree required; MBA or other advanced degree preferred.

Leadership Expectations

• Demonstrates a deep commitment to patients and the rare disease community.

• Operates with integrity, accountability, and strong collaboration.

• Leads with an enterprise mindset, prioritizing overall franchise success over functional optimization.

• Drives innovation and continuous improvement in marketing capabilities.

• Acts as a trusted partner to the VP, Head of U.S. ET and the broader leadership team.

Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.

Equal Opportunity Employer/Veterans/Disabled

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability