You will be responsible for:

Value

• Lead and drive cross-functional development of a clear, differentiated value proposition for NMOSD, while influencing without authority and navigating complex organizational systems.

• Collaborate with cross-functional teams to ensure that evidence generation plans and real-world evidence (RWE) are incorporated effectively to deliver a comprehensive value proposition, reduce uncertainty for payers, and optimize patient access. This includes securing timely country input on endpoints and evidence generation plans in priority target countries.

• Provide support to the GMMA Commercial team to advance NMOSD lifecycle management (LCM) through governance milestones focused on market access potential, evidence, and target product profile (TPP) requirements.

Access

• Leaddevelopment ofglobal market access and pricing strategies-activitiesandsupport implementationin close partnership with country access representativesofassigned countries

• Lead the assessment of pricing and reimbursement (P&R) risks and opportunities, and the implementation of corresponding mitigation actions specific to Neurology

• Create and roll out strategic value, access, and pricing communication tools and materials for NMOSD to support local P&R submissions and negotiations, such as pricing frameworks, negotiation strategies, and toolkits, in alignment with the enterprise-wide launch framework.

• Lead the update of the global reimbursement dossier for NMOSD and the overall cross-functional market access readiness plans for Neurology, in close collaboration with key countries and support functions (HEOR, Medical, and Commercial).

• Represent the GVAP perspective and strategy across various cross-functional teams, including the Global Value Sub-Team and Global Launch Team, and provide updates and guidance to local teams as needed.

• Own the monthlyNeurologypayer working group to share the latest evidence and drive best practice sharing across countries.

• Understand and incorporate thepatientperspective on thedisease, andrecommend strategies that support thepatientvoice in key payer negotiations.

Pricing

• Support the development ofthe Neurologypricing strategy.

• Conduct payer and value assessments to identify key market-specific P&R drivers and barriers, develop differentiated value propositions, and inform evidence generation plans, regulatory strategy, and development decisions.

• For the top EU Neurology markets, lead and co-create market-level P&R strategies and support P&R submissions and negotiations to drive positive outcomes.

• Review P&R cases submitted bymarkets, andsupport markets in maintaining value while unlocking local accessworking in close partnership with country access representatives and /or access International shared marketsGVAPteam for relevant countries.

• Offer critical strategic input to inform access and pricing assumptions, enabling accurate, market-driven LTP assumptions.

• Communicate effectively with GMMA senior leadership and other key stakeholders, particularly in relation to Neurology launches and NMOSD LCM P&R strategy.

You will need to have:

• Demonstratedleadership andtheability to take initiative and consistently deliver high-quality workin the context of rarediseases evidence, where there is greateruncertainty andcompetiiton

• The abilitytocommunicate effectivelyand translatescience into compellingpayer value story benefitsfor Alexionleadership and other identified stakeholders,including close collaborationwithlocal market access colleagues and the Commercial Launch Excellence function.

• Experiencedevelopingevidence-based innovative value solutions,for examplethrough working with local payers intheEU or commercial customers in the US.

• A relevantgraduate degree, such as aPhD, PharmD,BiomedicalSciences, business, or economicsqualification.

• Highly specialized rare diseaseandor Neurologymarket access experience

• More than 6 years of relevant drug development and/or commercialization experience within the pharmaceutical/medical industry

• Knowledge of the needs and expectations of national and regional payers, insurers, and commercial customers in our strategic marketsKnowledge and experience in keycost-effectivenessmarkets, such as theUK, Canada andtheNordics,is preferred.

• The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without accommodation,touse a computer; engage in communications via phone, video, and electronic messaging; engage in problem-solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.