Job Title: Senior Medical Director, Global Clinical Development(Infectious Disease/Pulmonology)

Hybrid role: 3 days per week in the office

Location: Gaithersburg

Are you a clinical research expert ready for new opportunities? Would you like to play a pivotal role in the development of potential medicines? If you are passionate about being a medical leader for a cross-functional team in a group that drives action towards the improvement of global public health– join us! AsSenior Medical Director,you will have a unique opportunity to further elevate the Infectious Disease Therapy Areawith your pulmonologyexpertisein one of the world’s most respected biopharmaceutical companiesThe role holds a significant development opportunity for the successful candidate whilst contributing to the positive journey that AstraZeneca is on.

Accountabilities

• Providing medical and scientific leadership in the global development of new medicines targeted at indications in the field of infectious diseases

• Help design, execute, and interpret clinical trials in one or more development programs (Phase 1 through Phase 3)and present the clinical strategy at internal governance meetings

• Lead the Clinical Team andwork closely withothercolleagues in other internal functions including Patient Safety, Biometrics, Regulatory Affairs, and Clinical Operations

• Build strong relationships with a network of external scientific specialists and opinion leaders

• Medical oversight to ensure the safety of study participants including review of Adverse Events of Special Interest and Serious Adverse Events and review and writing of safety narrative reports

• Provide expert medical input and write clinical study documents such as protocols,study reports, andregulatorysubmissiondocuments and responses

• Provide expert medical and scientific analysis and interpretation of data from ongoing studies and inthe literature

• Prepare publications and presentations for scientific meetings and congresses

Essential Skills/Experience:

• Graduate of a recognized school of medicine with an MD degree or equivalentwithboard-certification inpulmonology

• Demonstrated clinical researchexpertiseinthe field of pulmonology (especially in COPD and bronchiectasis)

• Pharma industry experience in clinical drug developmentfor at least2.5years

• Developed/delivered in parallel, composed of multiple complex and large studies (e.g., including but not limited to multinational, pivotal Phase 3 efficacy studies)

• Demonstrated ability to lead the development of a program strategy(e.g., Clinical Development Plans)and be accountable for project plans, timelines, progress, and outcomes

• Experience inthe design, execution, and interpretation of clinical studies (e.g., medical monitoring, data cleaning)

• Demonstrated ability leading and motivating teams in a matrix environment

• Demonstrated ability to lead, coach, and mentor physiciansand scientists

• Demonstrated ability to cultivate excellent cross-functional collaborations

• Demonstrated ability to effectively communicate at multiple levels of the organization

• Mustdemonstratehigh integrity

• Organize and deliver Advisory Boards with international Key Opinion Leaders (KOLs)

• Demonstrated AI/digital mindset and experience applying AI-enabled and generative AI tools to support clinical development activities (e.g., data analysis, medical writing, clinical trial operational efficiency)

• Excellent verbal and written communication skills (including giving presentations) in English

• Be office based atthe GaithersburgAstraZeneca siteat least 3 days a week

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work atpaceand challenge perceptions.That’swhy we work, on average, a minimum of three days per week from the office. But thatdoesn'tmeanwe’renot flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca?

We are a changemaker on the world stage at an exciting frontier of medicine. This is backed by deep knowledge and experience in our field. Building on this, we lead the way into the future with energy and drive. We are helping to transform healthcare and build pandemic preparedness to protect against future health crises and to bring lasting immunity to people around the globe. We are committed to ourcentral rolein addressing pandemic and endemic diseases and ensuring our products continue to reach andbenefitmillions of people around the world.

The annual base pay (or hourly rate of compensation) for this position ranges from $288,059.20 - 432,088.80 Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.