Manifold Bio is a dynamic biotech company building a pipeline of targeted biologics using a novel in vivo-centric discovery approach. Our drug discovery engine is differentiated by massively parallel screening in vivo from the beginning of our discovery process. This unique platform is powered by a proprietary protein barcoding technology that allows multiplexed protein quantitation at unprecedented scale and sensitivity. We combine this and other high-throughput protein engineering approaches with computational design to create antibody-like drugs and other biologics.Our world-class team of protein engineers, biologists, and computational scientists are working together to aim the platform at therapeutic opportunities where precise targeting is the key to overcoming clinical challenges.
Position
Come join Manifold as our first full-time People & Talent professional, reporting to the COO. Fueled by a new research collaboration with Roche, we are in the midst of a rapid growth spurt from 35 to 60+ employees, and will be looking to you to help us scale gracefully and efficiently while maintaining all that we love in our onsite culture. You ideally have startup experience in discovery stage biotech, though experience scaling a successful tech company would also be relevant. The ability to flex between talent acquisition, development, employee relations, and compensation planning, and are curious about ways to use technology like Greenhouse, Google Workspace, and AI applications to make life easier. You balance empathetic people leadership with sharp business judgment and creative problem-solving.
Responsibilities
Qualifications
We value different experiences and ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.

Manifold Bio is positioned to be the leading tissue-specific medicines company.
We’ve built the first high-throughput in vivo (HTV) discovery engine - combining massively multiplexed in vivo screening and AI-powered design to create targeted biologics. Our engine sculpts pharmacokinetics, biodistribution, and other key properties of biologics directly in living systems, solving previously intractable challenges for tissue-specific delivery.
By generating rich, scalable datasets in vivo, Manifold Bio is unlocking AI’s full potential to design targeted, effective therapeutics, and accelerate their path to patients.