Immatics

Director, Facilities, Engineering, and Maintenance

Immatics  •  Houston, TX (Onsite)  •  2 months ago
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Job Description

JoinImmaticsandshape thefuture ofcancerimmunotherapy; one patient at atime!

Immaticsis committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Ourcutting-edgescience and robust clinical pipeline form the broadest PRAMEfranchise with the most PRAMEindications and modalities, spanning TCR T-cell therapies and TCRbispecifics

Why Join Us?

  • Innovative Environment:Help topioneeradvancementsin cancer immunotherapy.

  • Collaborative Culture:Be part of a diverse team dedicated to your professionalgrowth.

  • Global Impact:Contribute to therapies thatmakealasting impactonpatientsglobally

We are seeking an experienced and forward-thinking Director of Facilities, Engineering & Maintenance to lead all aspects of our US facility operations, engineering strategy, and infrastructure development across our GMP manufacturing and research environments. This role is critical to ensuring our US facilities operate safely, reliably, and in full compliance with regulatory standards. The ideal candidate brings deep technical expertise in biotech or pharmaceutical facility operations, strong leadership capabilities, and a passion for building high performance teams and systems.

FLSA ClassificationSalaried, Exempt 
Schedule 8:00 AM – 5:00 PM; Monday to Friday; On-site 
Reports toChief Operating Officer
Location 13203Murphy Road,Suite 100,Stafford, TX 77477 

WhatYou’llDo:

As aDirector of Facilities, Engineering & Maintenance, you will play a key role in supporting ourUS facilityoperations: 

  • Develop and execute the long-term facility engineering & maintenance strategy to support company growth, GMP manufacturing capacity, and R&D operations.

  • Accountable for scaling the facility infrastructure for commercial manufacturing,inspectionreadiness, uptime and cost-efficient operation

  • Lead capital planning, budgeting, and prioritization for facility upgrades, expansions, and construction

  • Serve as the primary engineering advisor to senior leadership, providing insights on infrastructure readiness, risk, and operational performance

  • Oversee the operation, maintenance, and lifecycle management of all critical building systems, including HVAC, clean rooms, utilities, automation, and process equipment.

  • Ensure uninterrupted operation of GMP and laboratory facilities through robust preventive and predictive maintenanceprograms, andestablishing an alarm escalation chain

  • Establish engineering standards, SOPs, and best practices to ensure consistent, compliant, and efficient facility operations.

  • Ensure all facility systems meet regulatory requirements (FDA, EMA, ISO, cGMP, CLIA) and maintain audit readiness.

  • Partner with Quality Assurance to manage deviations, CAPAs, change controls, and validation activities related to facility infrastructure.

  • Partner with Computer System Validation to manage validation of new equipment.

  • Oversee qualification and validation of utilities and equipment (e.g., HVAC, WFI, clean steam, compressed gases, BMS/EMS).

  • Lead the planning, design, and execution of facility engineering projects, including cleanroom builds, utility upgrades, and equipment installations.

  • Manage external engineering firms, contractors, and vendors to ensure projects are delivered on time, within budget, and to specification

  • Implement strong project governance, documentation, and risk management practices.

  • Responsible for EHS-related compliance on site

  • Ensure site security

  • Drive sustainability initiatives related to energy efficiency, waste reduction, and environmental impact.

  • Oversee emergency response systems, business continuity planning, and facility risk assessments for the facilities, engineering & maintenance department.

  • Build, mentor, and lead high performing multidisciplinary engineering team.

  • Foster a culture of accountability, continuous improvement, and cross functional collaboration.

  • Develop training programs to ensure staff competency in GMP, safety, and technical disciplines.

  • Oversee vendor relationships for facility services, maintenance contracts, and engineering support.

  • Negotiate service agreements and ensure vendor performance meets operational and compliance standards.

  • Manage departmental budgets, cost controls, and resource allocation.

RequiredExperienceandEducation

  • Bachelor’s degree in Engineering (Mechanical, Electrical, Chemical, or related field).

  • 10+ years of facilities, engineering & maintenance experience in biotech, pharmaceutical, or other regulated life science environments.

  • 5+ years of leadership experience managing engineering or facility operations teams.

  • Demonstrated experience in at least some of the following: leading GMP facility start-up or expansion projects, managing critical utilities and cleanrooms in regulated manufacturing, running maintenance/reliability programs, handling audits/inspections, and building teams in a fast-growth biotech environment.

  • Strong knowledge of GMP regulations, cleanroom operations, and critical utilities.

  • Proven experience leading capital projects and managing external contractors.

  • Demonstrated ability to operate in fast-paced, high-growth environments.

  • Must be authorized to work in the U.S.

PreferredExperienceandEducation

  • Experience with facilities, engineering & maintenance in a commercial-stage cGMP environment

  • Master's degree in engineering, Facilities Management, or related discipline.

  • Experience in cell therapy, biologics manufacturing, or advanced therapy medicinal products (ATMPs).

  • Certification in Project Management (PMP), Facilities Management (CFM), or similar.

  • Experience with state-of-the-art BMS/EMS systems, ERP systems, MES systems, LIMS systems, automation platforms, digital maintenance systems and regulatory asset management systems.

Competencies

  • Initiative

  • Problem Solving

  • Critical Thinking

  • Interpersonal Communication

  • Customer Service

  • Attention to Detail

Work Environment:

This is a sedentary position (at least 50% oftime) in a typical office environment. There may be frequent interruptions with moderate noise levels and frequent use of printers, copiers, scanners,computersand other office equipment.Abilityto sit, talk, walk,hearand communicate verbally and in writing isrequired Occasional lifting of objects up to 25lbs.is expected.   

Travel required:up to10%travelrequired, domestically and internationally

Physical demands:

  • Communicating Verbally– expressing or exchanging ideasby means ofthe spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately,loudlyor quickly.

  • Hearing– the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds.

  • Keyboarding– entering data or text into a computer or other machine by means ofa keyboard.Devices include a traditional keyboard, 10key-pad, touchscreensand others.

  • Lifting- raising or lowering an object (up to 25lbs) from one level to another (includes upward pulling). Carrying is to transport an object – usually by holding it in the hands or armsbutmay occur on the shoulder.

  • Near Visual Acuity– clarity of vision at approximately 20 inches or less (working with small objects, reading small print, including the use of computers).

  • Pushing- Exerting force upon an object so that the object moves away from the object.

  • Pulling- Exerting force upon an object so that the object moves toward the force.

  • Sittingremainingin a sitting position for at least 50% of the time.

  • Standing/Walking- remain on one's feet in an upright position at a workstation.

  • Stoopingoccasional bendingthe body downward and forward by bending the spine at the waist - requiring full use of the lower extremities and back muscles.

Work authorization/security clearancerequirements

Legal eligibility to work in the United States isrequiredImmaticsparticipates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment

Affirmative Action/EEO statement

Immaticsis an equalopportunityemployer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.

What do we offer?

AtImmatics, we believe in investing in our team’s health,safetyand well-beingHere’swhat you can expectif youjoinImmatics

Comprehensive Benefits

  • Competitive rates forHealth, Dental, and Vision Insurance

  • 4 weeks ofPaid Timeoff, granted up front each year and prorated for firstand lastyear ofemployment.

  • Sick Time Off7days

  • 12Paid Holidays

  • 100%Employer-Paid Life Insurance up toat 1x annual salary, up to one hundred thousand dollars

  • 100%EmployerPaidShort- and Long-Term Disability Coverage 

  • 401(k) with ImmediateEligibility &company match…

  • You are eligible for 401(k) plan participation as of your first paycheck.

  • The company will match100% of your contributions upto3% of yourbase salaryfor the first two yearsof employment, 4% foryears 2-3 of employment, and up to5%of your salaryfrom the fourth year onward of continued employment.

  • PartiallypaidParentalLeave for eligible employees.(3 weeks)

  • Additionalvoluntary employee paidcoveragesincluding Accident, Hospital Indemnity, and Critical Illness Employee PaidIdentity Theft Protection and Pet Insurance

Professional Growth

  • Opportunities to work with leading experts in the field of T-cell immunotherapy.

  • Company provided learning and development opportunities

  • Fast paced,highdemandcollaborative and dynamic environment.

Immatics

About Immatics

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Read more about Immatics on our homepage: https://immatics.com/

Find us also on:

Instagram: https://www.instagram.com/immatics/

YouTube: https://www.youtube.com/channel/UCv7uTpsGXvSNzwSX_xOtYSA

Legal notice: https://immatics.com/imprint/

Industry
Biotech & Life Sciences
Company Size
501-1,000 employees
Headquarters
Tuebingen, DE
Year Founded
2000
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