
The Director, Evidence Generation Systems is an individual contributor responsible for hands‑on ownership, delivery, and evolution of one or more core Evidence Generation systems within the broader Evidence Generation systems ecosystem, while also shaping and leading complex capabilities that span multiple interdependent systems.
This role operates at the intersection of strategy execution and system delivery. The Director translates Evidence Generation business priorities and strategic intents into cohesive, executable system designs, drives delivery across tightly connected platforms and external dependencies, and resolves complex integration, compliance, and delivery challenges. The role is deeply hands‑on, with a strong emphasis on making strategic roadmap priorities real through disciplined execution, particularly during periods of system stand‑up, modernization, and ecosystem integration.
The Director reports to the Senior Director, Evidence Generation Systems Lead and is accountable for executing and operationalizing roadmap priorities across assigned system(s) and cross‑system capabilities, ensuring solutions are delivered in a compliant, integrated, scalable, and operationally ready manner.
Role Responsibilities
Own hands‑on delivery, operationalization, and continuous improvement of one or more core Evidence Generation systems, from requirements through release and hypercare, with a focus on long‑term sustainability and scalability.
In addition to system ownership, lead strategically important cross‑system capabilities spanning multiple interdependent Evidence Generation systems and external dependencies.
Translate end‑to‑end Evidence Generation business priorities and roadmap intents into aligned functional requirements, system designs, and integration approaches across systems.
Ensuring delivery aligns with roadmap priorities and business outcomes (backlog readiness, sprint execution, and release activities), in close partnership with Pfizer Digital and external vendors.
Lead and orchestrate system‑level and cross‑system integrations and dependencies, including upstream and downstream systems outside direct control, balancing delivery risk, compliance, and business impact, in close partnership with Pfizer Digital and external vendors.
Define and execute system‑level and cross‑system training, user enablement, and communication strategies to support adoption, change, and sustained value realization.
Act as a senior system owner and escalation point for issue resolution, release stabilization, and continuous improvement across assigned systems.
Execute assigned roadmap initiatives, proactively managing dependencies, sequencing, and delivery risks, and surfacing strategic implications through governance forums.
Work closely with cross‑functional stakeholders including IEG, Medical & Scientific Evidence Generation Operations, Medical Affairs, HV&E, Clinical Development, Regulatory, Safety, Compliance, Digital, and external vendors to ensure solutions are strategically aligned, operationally fit, and compliant.
Education and Experience
Basic Qualifications:
Bachelor’s degree in Life Sciences, Information Systems, Engineering, or a related field with 9+ years of relevant experience delivering and owning regulated enterprise systems
OR
Master’s degree in a relevant field with 7–9 years of relevant experience
OR
PhD, PharmD, MD or equivalent doctoral degree with 4–6 years of relevant experience
Experience working in matrixed teams with cross-functional collaboration and vendors.
Solid understanding of Evidence Generation processes, system interdependencies, and end‑to‑end lifecycle considerations.
Working knowledge of GxP and compliance expectations in the pharmaceutical industry.
Demonstrated ability to influence senior stakeholders, manage ambiguity, and drive outcomes across matrixed organizations.
Preferred Qualifications:
Demonstrated hands‑on experience owning one or more enterprise systems and leading delivery of complex, cross‑system capabilities in a regulated environment.
Proven ability to translate complex business workflows into executable system designs, requirements, and integration approaches.
Experience owning or modernizing Evidence Generation systems.
Familiarity with workflow‑based enterprise platforms (e.g., Salesforce‑based or equivalent ecosystems).
Experience leading multi‑system integrations involving financial, resource, or operational systems outside direct control.
Strong analytical and problem‑solving skills, with the ability to assess trade‑offs across compliance, risk, usability, and delivery timelines.
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Work Location Assignment:
This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.
The annual base salary for this position ranges from $162,900.00 to $271,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to makewww.pfizer.com/careersaccessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please emaildisabilityrecruitment@pfizer.com This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
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