Job Description

Who We Are

BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health.

Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities.

Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best – people with the right technical expertise and a relentless drive to solve real problems – and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we’ve produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options.

About Worldwide Research and Development

From research and discovery to post-market clinical development, our R&D engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with rare diseases.

CONTRACT ROLE Position is on-site 5 days a week in San Rafael***

Senior Research Associate – Formulation & Analytical Support

We are seeking a highly skilled Senior Research Associate to provide formulation and analytical support for oligonucleotide based therapeutics across in vitro and in vivo studies. This individual will work both independently and collaboratively to ensure high quality dosing solutions, execute stability testing, support analytical workflows, and contribute to nonclinical and clinical development programs.

Key Responsibilities
Formulation & Dosing Support
• Independently and collaboratively prepare, formulate, and quality check dosing solutions for a range of in vitro and in vivo studies
• Perform formulation stability studies and define appropriate short and long term storage conditions
• Support formulation strategies for oligonucleotides across different delivery and study paradigms

Analytical & Technical Support
• Execute analytical assays to support formulation and quality assessment, including UV, LC MS, and osmolality measurements
• Perform quantitative data analysis across multiple experiments, including basic statistical and graphical analysis
• Proactively troubleshoot technical issues and recommend corrective actions to ensure data quality and project continuity

Innovation & Capability Building
• Develop new techniques or introduce new technologies to enhance the group’s formulation and analytical capabilities
• Contribute to continuous improvement of laboratory workflows and experimental approaches

Documentation & Communication
• Maintain accurate and thorough laboratory notebook records in compliance with data integrity standards
• Prepare SOPs, technical reports, and documentation to support nonclinical and clinical programs, including regulatory submissions
• Present data and actively participate in group meetings, department meetings, and Early Development team meetings

Laboratory Operations
• Share responsibility for laboratory management duties, including equipment readiness, inventory, and general lab organization

Required Skills & Experience
• Good understanding of oligonucleotide therapeutics, formulation approaches, and stability testing
• Hands on experience with analytical techniques such as UV spectroscopy, LC MS, and osmolality measurements
• Ability to perform quantitative analysis across studies with minimal supervision
• Demonstrated ability to work independently while contributing effectively within cross functional teams
• Strong problem solving skills and attention to detail

Education & Qualifications
• Bachelor’s degree in Chemistry, Pharmaceutical Sciences, Biochemistry, or a related field with 6+ years of relevant experience, or
• Master’s degree with 4+ years of relevant experience

Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned.

Equal Opportunity Employer/Veterans/Disabled

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.