Vertex is seeking a talented individual to join our Engineering and Materials Sciences group in Boston, MA on a temporary contract basis.
Engineering and Materials Sciences at Vertex plays a vital role in bridging the gap between new pharmaceutical discoveries and commercial products. Engineers at Vertex work in multidisciplinary scientific teams to bring basic medical discoveries to patients and physicians by applying fundamental chemistry and chemical engineering principles to new products, processes, and development technologies.
The successful candidate will be a highly productive, results-oriented individual, able to generate and implement original ideas and solutions that contribute materially to the success and development of drug substance candidates. Strong communication, organization, and planning skills and a high level of technical aptitude and creativity are required for success in this position.
The successful candidate will be responsible for:
• Supporting drug substance process development on a laboratory/bench scale, and in particular, developing and demonstrating early fit-for-purpose API crystallizations leading to commercially viable API particle forming processes. These would include the development of crystallization, isolation, drying, size reduction and other particle engineering operations.
Basic and Preferred Qualifications include:
• MS/BS degree with 2 - 5 years of pharmaceutical industry experience. Degrees with a life science concentration required, with a preference for concentrations in chemical engineering or chemistry.
• Knowledge and experience in API process development and scale up, in particular small molecule crystallization and particle engineering operations.
• A demonstrated understanding and working knowledge of chemistry and chemical engineering fundamentals; applied kinetics, thermodynamics, and transport fundamentals; as well as familiarity with modern laboratory instrumentation (HPLC, GC, FTIR, Raman, FBRM, DSC, TGA, XRPD, etc) and common laboratory automation tools.
• Experience with statistical design of experiments; QbD concepts; and familiarity with common physical property and process modeling tools (Aspen, Dynochem, Matlab, etc.).
• The ability to successfully interact and collaborate within an interdisciplinary team environment comprised of organic, physical, and analytical chemists, project team members, and manufacturing personnel.
• Proven communication (verbal and written) and interpersonal skills.
$60-$63/HR
This job posting is for a temporary role with a third-party agency partner on assignment at Vertex Pharmaceuticals (“Vertex”). The individual selected for this role will be offered the role as an employee of a third- party agency partner; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency partner upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on a number of factors, including skills, competencies, experience, location and/or being pursued and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements
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If you do not agree with the Atrium Terms and Conditions, you can still complete your application for this position by emailing your resume to our team at tempstaffing@vrtx.com. Please include the job title in the subject of your email.
No C2C or Third-Party Vendors
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and have made significant advancements in multiple chronic, life-shortening genetic diseases — cystic fibrosis, sickle cell disease and transfusion-dependent beta thalassemia — and continue to progress clinical and research programs in these diseases. We also have a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where we have deep insight into causal human biology, including acute and neuropathic pain, APOL1-mediated kidney disease, IgA nephropathy, autosomal dominant polycystic kidney disease, type 1 diabetes, myotonic dystrophy type 1 and alpha-1 antitrypsin deficiency.
Our global HQ is in Boston, and we have research and development (R&D) sites and commercial offices worldwide.
Vertex is consistently recognized as one of the industry’s top places to work by Science Magazine, The Boston Globe, Boston Business Journal and the San Diego Business Journal. We have also earned a spot on TIME Most Influential Companies, TIME Best Inventions, and Fast Company Most Innovative Companies lists. Our research and medicines have received esteemed recognitions, including the Robert J. Beall Therapeutics Development Award, the Prix Galien, the Scrip Award and the Breakthrough Prize awards.
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