Local Trial Manager (Home‑Based) – Australia | Embedded Sponsor Model
ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
Location: Home‑based anywhere in Australia
As a Local Trial Manager (LTM), you will join the world’s largest and most comprehensive clinical research organisation, powered by healthcare intelligence. This role sits within a fully embedded model supporting a leading global pharmaceutical organisation, working on complex and high‑profile clinical trials.
You will partner closely with local study stakeholders, taking full accountability for the end‑to‑end delivery of clinical trials within Australia, with a strong focus on quality, compliance, and execution excellence.
Provide local leadership and oversight for clinical trials from start‑up through to close‑out in accordance with ICH‑GCP, local regulations, and company SOPs
Act as the primary local trial lead, ensuring successful country and site‑level delivery aligned with the global project plan
Deliver proactive study risk management across Australian studies, identifying, mitigating, and escalating risks appropriately
Lead and influence a regional matrix team, driving performance, accountability, and timely execution of study milestones
Partner closely with clinical operations, regulatory, safety, and vendors to ensure delivery on time and within budget
Maintain TMF quality, completeness, and inspection readiness
Tertiary qualification in Life Sciences, Healthcare, or a related discipline
Recent and demonstrated clinical trial leadership experience in Australia, operating in a PM / CTM / LTM role (min. 2 years) within pharma/ biotech or CRO
Strong Oncology and/or Hematology experience, ideally as CTM/ PM across complex, multi‑site trials
Proven ability to work autonomously, manage multiple priorities, and drive delivery in a fast‑paced environment
Strong stakeholder management, communication, and influencing skills
High attention to detail with a strong quality and compliance mindset
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Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here
Are you a current ICON Employee? Please click here to apply
Since our foundation in Dublin, Ireland in 1990, our mission has been to help our clients to accelerate the development of drugs and devices that save lives and improve quality of life. We do this by delivering best in class information, solutions and performance, with an unyielding focus on quality at all times.
We offer a full range of consulting, development and commercialisation services from a global network of offices in 53 countries. We focus our innovation on the factors that are critical to our clients – reducing time to market, reducing cost, and increasing quality – and our global team of experts has extensive experience in a broad range of therapeutic areas.
