Job Description

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Duke Cancer Institute’s Gastrointestinal (GI) Clinical Research Program is seeking a Clinical Research Nurse Coordinator to support the successful execution of complex oncology clinical trials within the Oncology Clinical Research Unit (CRU). In this role, you will play a critical part in advancing cancer research by coordinating multiple studies involving investigational products while ensuring high-quality patient care and regulatory compliance.

In your day-to-day work, you will collaborate closely with Principal Investigators (PIs), sponsors, and interdisciplinary teams to recruit, enroll, and manage study participants. You will help patients navigate clinical trial participation, provide education on study medications and procedures, and ensure safety through careful monitoring and documentation.

This position offers the opportunity to directly impact cutting-edge oncology research while combining clinical nursing expertise with research operations, data management, and leadership responsibilities.

Minimum Requirements:

• Graduation from an accredited BSN, ADN, or Nursing Diploma program
• Current RN licensure in North Carolina (or compact state)
• BLS certification required
• Twelve months of appropriate clinical nursing experience
• Ability to maintain compliance with hospital and unit-specific training competencies and NCBON requirements
• Nurses without a BSN are encouraged to enroll within two years and complete within seven years (exception applies to hires before September 1, 2016)

Preferred Qualifications:

• Oncology nursing experience
• Clinical research experience, particularly in oncology trials
• Experience working with investigational products and clinical trial protocols

Other Requirements:

• Ability to maintain required certifications and training for clinical research and nursing practice
• Strong understanding of regulatory, compliance, and ethical requirements in clinical research
• Participation in ongoing continuing education and professional development
• This position is onsite, with work performed at designated Duke clinical and research locations

Be Bold.

Position Responsibilities:

• Lead and coordinate complex oncology clinical trials, including study feasibility, recruitment, enrollment, and retention strategies
• Recruit, screen, consent, and manage study participants, ensuring adherence to protocol requirements and patient-centered care
• Conduct and document study visits, including clinical assessments, adverse event monitoring, and patient education on study medications and side effects
• Administer medications and chemotherapy, review laboratory results, and provide clinical interventions as guided by the Principal Investigator
• Maintain study compliance with institutional policies, regulatory requirements, and protocol standards, including accurate documentation in regulatory binders and systems of record
• Record and report adverse events (AE) and ensure timely escalation of study and patient care issues
• Coordinate study startup, site initiation, and closeout activities, and assist with development of new clinical research studies
• Manage study documentation and regulatory processes, including Delegation of Authority Logs, COI disclosures, DSMPs, and RDSPs
• Collaborate with financial teams to monitor study milestones, assist with budgets, track study payments, and support study closeout processes
• Serve as a primary liaison between sponsors, PIs, and study teams, ensuring clear, timely, and professional communication
• Enter and manage clinical trial data in Electronic Data Capture (EDC) systems, ensuring accuracy, completeness, and data integrity
• Identify and resolve data discrepancies while maintaining data security and compliance standards
• Provide leadership and mentorship to team members, serving as an expert resource and supporting team development and project completion
• Participate in committees, task forces, and professional development activities, including scientific presentations and publications
• Ensure ethical conduct of research, educating participants and staff on distinctions between clinical care and research, including risks and benefits of participation
• Follow all SOPs, institutional policies, and regulatory requirements governing clinical research activities

RN-Specific Responsibilities:

• Ambulatory medication administration
• Adult chemotherapy administration
• Medication management and patient education
• Review and interpret clinical laboratory results
• Basic dysrhythmia review
• Assess patients for adverse events and compliance, and implement appropriate interventions
• Collaborate effectively with the clinical care team

Choose Duke.

Join Duke University’s world-renowned Duke Cancer Institute, where innovation, discovery, and patient-centered care drive everything we do. As part of the GI Clinical Research Program, you will contribute to groundbreaking oncology research that directly impacts patient outcomes and advances the field of cancer treatment.

At Duke, you’ll work alongside leading clinicians, researchers, and healthcare professionals in a collaborative and inclusive environment that values excellence and continuous learning. You’ll have opportunities to grow your career, expand your clinical and research expertise, and contribute to meaningful scientific advancements.