Job Description

We are actively building a talent pipeline for Clinical Research Associate positions within our Biopharma and Oncology teams in Sydney, with recruitment anticipated later in 2026.

If you’d like to be among the first to hear about these upcoming roles, we invite you to join our Talent Network. By registering, you’ll gain access to early notifications of vacancies, networking opportunities, and tailored insights to support your career development.

Stay connected with us and secure your chance to be part of our future hiring initiatives.

At AstraZeneca, we’re united by a bold ambition: to transform patients’ lives through science. Across BioPharma and Oncology, we design and deliver high‑quality, patient‑centric clinical trials that translate deep biology into breakthrough medicines in cardiovascular, renal & metabolism, respiratory & immunology, and cancers where the need is greatest.

As a Clinical Research Associate, you will own site activation and performance, direct risk-based monitoring to where it matters most, and safeguard patient safety and data integrity. You will partner with investigators, shape inspection readiness, and apply a forward-looking approach that challenges the status quo and accelerates launches. How will you use your judgment and influence to turn a promising protocol into a reliable, scalable trial outcome.

What you’ll do

• Identify and evaluate sites and investigators, build collaborative relationships, and drive activation, enrolment and sustained performance.
• Coordinate EC/IRB and health‑authority submissions, secure and maintain approvals, and manage essential documents to keep studies inspection‑ready from day one.
• Train and support site teams on ICH‑GCP and RbQM, embed compliance routines, and coach toward audit and inspection readiness.
• Conduct remote and onsite monitoring visits; perform Source Data Review (SDR), Source Data Verification (SDV) and Case Report Form (CRF) review; manage data queries; and adjust monitoring intensity based on risk signals.
• Ensure timely reporting of Serious Adverse Events (SAEs); proactively identify, escalate and resolve quality issues in line with AstraZeneca SOPs.
• Maintain CTMS and eTMF accuracy; manage study drug supplies and accountability; and deliver clear, timely monitoring reports and follow‑up.

Essential for the role

• Bachelor’s degree in a life science or related field (or equivalent experience).
• Solid understanding of the drug development process, ICH‑GCP and relevant country regulations.
• Experience in site selection, activation and monitoring (remote and onsite) with strong documentation discipline.
• Proficiency with CTMS/eTMF and data‑query management; familiarity with SDR/SDV/CRF review.
• Strong communication, stakeholder management and problem‑solving skills; ability to work independently and as part of a cross‑functional team.
• Willingness to travel for site monitoring; fluency in written and spoken business‑level English.

Desirable for the role

• Experience across CVRM or Respiratory & Immunology trials, including multi‑country studies.
• Hands‑on use of RbQM analytics/dashboards to prioritise monitoring and remediation.
• Proven contribution to accelerated start‑up timelines and efficient site activation.
• Confidence in audits/inspections; track record coaching sites to readiness.
• Comfort with remote monitoring tools, eSource/ePRO and data‑driven decision‑making.
• Fluency in the local language in addition to English.

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

Join Our Talent Network

Please join with a resume outlining your suitable experience or just your name and contact details if you don't have a resume handy and we'll follow up after the event to get your resume.

Where can I find out more?

Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
Visit our website: www.astrazeneca.com.au

AstraZeneca in Australia has been formally recognised as an Employer of Choice for Gender Equality by the Workplace Gender Equality Agency (WGEA) and as a Gold Tier Employer within the Australian Workplace Equality Index (AWEI). Visit our ANZ Careers Page - www.astrazeneca.com.au/careers.html to learn more about our commitment to fostering a flexible, diverse, and inclusive environment.

We recognise that any recruitment process may present challenges, if there is anything we can do to make our recruitment process more accessible for you, please let us know via this Form

Date Posted

09-June-2026

Closing Date

12-June-2026

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.