
EQL Tech is partnering with Sentinel Bio to find an exceptional Chief Operating Officer to join its leadership team as the organization scales toward deploying more than $100M toward its mission by 2030.
Sentinel Bio is dedicated to making pandemics history within our lifetimes — finding, funding, and scaling the most promising efforts to eliminate catastrophic pandemics over the coming decade. Since launching in 2024, Sentinel has played a central role as the biosecurity field has achieved significant milestones toward substantially mitigating pandemic risk. The organization has raised nearly $40 million in philanthropic capital and funded more than 70 grants, special projects, and incubated organizations focused on safeguarding AI-enabled biology and DNA synthesis.
The field stands at an inflection point: the threat of AI-enabled biotech misuse is accelerating dramatically, while new philanthropic resources create unprecedented opportunities to bolster societal resilience. With its track record and relationships across biosecurity, AI, and philanthropy, Sentinel is exceptionally well placed to seize this moment.
Sentinel is hiring an exceptional COO to build an organization that can deploy more than $100M by 2030. You'll own the internal architecture Sentinel needs at 2x, 5x, and 10x today's scale.
As a core member of the leadership team, you'll work closely with Sentinel's CEO, program leadership, and Operations Lead on organizational health. You'll represent Sentinel externally, and the team will trust you to make meaningful decisions independently.
Strategic leadership & organizational management
Partnership with program teams, grantees, and incubatees
People, culture & hiring
Finance & compliance
Sentinel is a small, high-trust team that moves quickly, takes its work seriously, and holds itself to a high standard. Impact on the mission is the bottom line — the North Star. When the path forward is unclear or difficult, the team turns to these guiding values:
Sentinel Bio is led by Claire Qureshi, who has over 15 years of leadership experience in biotech, global health, public policy, and consulting, and Joshua Monrad, who has deployed tens of millions of dollars in philanthropic grants and helped build several new biosecurity institutions. Sentinel has strong partnerships with a geographically diverse group of philanthropists who share its long-term mission, and is on track to raise and deploy $100M by 2030.
Sentinel Bio is building a team that reflects the global community it serves, embracing differences in background, perspective, and experience. The organization actively seeks out and welcomes talent from all walks of life, regardless of race, ethnicity, gender identity, sexual orientation, age, disability, or any other aspect that makes you uniquely you.
Requirements
The right person will be deeply mission-aligned, operationally excellent, and able to exercise mature judgment in ambiguous, high-stakes situations:
This role spans several domains, and no one candidate will be strong in all of them. That said, we're particularly excited about candidates who bring some combination of:
Benefits
Sentinel Bio has retained EQL Tech to lead this search. To apply, submit your CV and a few responses through this posting. We review applications on a rolling basis and aim to move quickly for strong candidates, who will be asked to complete a compensated work test. Initial conversations are confidential.

EQL Tech is the specialist recruitment partner to innovative AI native tech companies globally. We focus on scaling ventures through finding top talent across Sales, GTM & Engineering.
Incubated in Silicon Valley and growing from Austin & the UK, we work on a retained, exclusive and contingent basis to suit the needs of our diverse client partners, ranging from startup ventures to growth stage companies.