
Business Excellence Manager – Operational Transformation
Location: Onsite - Torrance, CA | Employment Type: Full-Time
Lead transformation. Drive performance. Shape the future. We’re seeking a Business Excellence Manager to own the site’s operational excellence roadmap and embed a culture of continuous improvement, digital maturity, and Lean leadership.This is a hands-on leadership role responsible for translating strategy into execution and driving measurable improvements in cost, quality, throughput, and operational performance.
This role is ideal for a leader who has implemented Lean in manufacturing environments, particularly in high-mix, custom, or made-to-order production settings where processes must adapt to changing customer requirements.
What You’ll Do:
Partner closely with the Site Director to execute strategic priorities and operational improvement initiatives
Lead and deliver end-to-end transformation projects with measurable impact on cost, quality, delivery, and throughput
Deploy Lean Six Sigma methodologies (Kaizen, Value Stream Mapping, root cause analysis) across production and support functions
Identify and eliminate bottlenecks in variable, non-standard production workflows
Establish, track, and improve KPIs and performance management systems that drive accountability at all levels
Drive adoption of digital tools, automation, and data analysis and visibility to support smarter decision-making
Facilitate Gemba walks, Kaizen events, and cross-functional problem-solving sessions
Coach leaders and frontline teams to embed a sustainable culture of continuous improvement
Standardize key processes while maintaining flexibility for customer-specific production requirements
What We’re Looking For:
Bachelor’s degree in Engineering, Operations, Business, or related field (MBA or advanced degree preferred)
10+ years of experience in manufacturing, operations, or operational excellence leadership.
Lean Six Sigma Green or Black Belt (Black Belt preferred).
Expertise in process optimization, KPI design, and digital tools.
Demonstrated success delivering tangible operational improvements (e.g., throughput, yield, cost reduction)
Direct experience leading shop-floor execution
Experience standardizing processes in variable production environments
Key Capabilities
Strong problem-solving skills with deep understanding of Lean tools and methodologies
Ability to balance structure and flexibility in complex manufacturing environments
Data-driven mindset with experience building and managing KPI systems
Proven ability to influence, coach, and drive change across all organizational levels
Excellent communication skills and strong executive presence
Why Join Us? Be the catalyst for operational transformation and deliver world-class performance in a fast-paced, regulated environment.
Salary: $120K - $170K
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.

PolyPeptide Group AG with its consolidated subsidiaries (“PolyPeptide”) is a focused Contract Development & Manufacturing Organization (CDMO) which specializes in the development and manufacturing of synthetic peptides and oligonucleotides used as active pharmaceutical ingredients (API) or intermediates in therapeutic products. It also produces a range of generic peptides and peptides used in cosmetics. The Group mainly serves pharmaceutical and biotech companies. By supporting its customers, PolyPeptide contributes to the health of millions of patients across the world. PolyPeptide provides its offering from pre-clinical through to commercial stages. Its active custom projects pipeline reflects the opportunities from novel drug therapies in development to fight both widespread and rare diseases. Established in 1952, PolyPeptide today runs a global network of six GMP-certified facilities in Europe, the U.S. and India. PolyPeptide’s shares (SIX: PPGN) are listed on SIX Swiss Exchange.
Find out more about our current vacancies at: https://polypeptide.teamtailor.com/