
AstraZeneca isseekinga highly motivated researcher to join the Process Development team, as Associate Scientist, supporting and contributing to the design and execution of studies to develop andoptimizeclinical manufacturing processes ofAstraZeneca’sportfolio of engineered T cell therapies.
As a member of the Process Development team, this rolewill alsosupporttechnology transfer to the clinicalproduction site.Based in Santa Monica, CA, this role reports to the Senior Scientist, Process Development.
Essential Functions and Responsibilities
Support experimental design and execute experiments to develop andoptimizemanufacturing processes for genome-engineered T cell products
Collect and analyze experimental data andpresentfindingsin team meetings Collaborate within the project team to interpret study results and contribute to technical discussions forsubsequentstudy design
Provide support across different process development areas during high-volume activitiesPrepare critical process materials including formulation of media and ribonucleic protein complexes.
Assistwith process development and tech transfer of GMP manufacturing processes to internal and external manufacturing organizations
Stay current with scientific advancements and emerging technologies in cell therapy process development. Help evaluatenew technologiesand methodologies to enhance process efficiency
Maintainaccurateand detailed laboratory notebooks and electronic records in compliance with company policies and regulatory requirements.
Assistin preparingtechnical documents, including standard operating procedures (SOPs), batch records, and development reports, as needed.
Work effectively in a team environment to meet projecttimelineandobjectives
Perform other duties as assigned.Position may require weekend work.
Required Skills
Hands-on experience with the development ofengineered TCRT cell therapies.
Hands-on experience with genome editing toolsincludingDNA/RNA transfection approaches.
Familiar with process development for cell therapies, including scale-up andinterpretation ofT-cellfunctional assayresults(flow-cytometry, cytotoxicity, proliferation)
Experience with authoring manufacturing batch records
Strong organizational and time management skills
Excellent teamwork and communicationskills,withthe ability to workcollaboratively cross-functionally
Proficiencywith MicrosoftOffice, including Word,Excel,Outlookand PowerPoint.
Desired Skills
Knowledge of cGMP manufacturing and practical experience in GMP operations.
Experience withstatistical analysis software (e.g.JMP, GraphPad Prism) for analyzing and presenting data.
Familiar with the fundamentals oftheDesign of Experiments approach
Education
BS or MS degree inBiology,Biotechnology, Biomedical Engineering, or related field with 1+ years of experience for MS or 2+ years of experience with BS
The annual base pay for this position ranges from $ 79,336.80 - $119,005.20 Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.
Date Posted
12-Jun-2026
Closing Date
29-Jun-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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