Job Description

The Pereira Laboratory at the Icahn School of Medicine investigates the neurobiology of Alzheimer's disease, including the selective regional and cellular vulnerability to tau pathology and neurodegeneration. We are seeking an outstanding Associate Scientist to join the lab's efforts to discover and validate novel therapeutic targets using animal models, postmortem human tissue, iPSCs, and bioinformatics.

• Perform in vivo experiments using mouse models, including stereotaxic injections.
• Conduct molecular and cell biology experiments to support ongoing research projects.
• Perform laboratory techniques, including cell culture, DNA/RNA isolation, cellular fractionation, Western blotting, PCR/qRT-PCR, in situ hybridization, and immunohistochemical labeling.
• Conduct research to develop methodologies, instrumentation, and procedures for medical applications, including analyzing data and presenting findings.
• Design and conduct complex research studies, evaluating alternative methods, computational models, and experimental approaches.
• Plan and conduct studies investigating human or animal diseases, preventive methods, and potential treatments.
• Assist in clinical laboratory operations, as needed.
• Follow established laboratory safety procedures to prevent contamination and ensure compliance with safety standards.
• Provide training and guidance on medical and laboratory procedures to physicians, residents, students, and research staff.
• Collaborate with healthcare professionals, researchers, and other stakeholders to support research initiatives and health safety standards.
• Develop research tools, techniques, and methodologies to support scientific investigations.
• Identify research questions, develop hypotheses, and establish methodologies for evaluating experimental results.
• Analyze and interpret research findings and communicate results through scientific publications and presentations.
• Develop research proposals and seek support for new and ongoing research activities.
• Provide scientific recommendations to support research activities and project objectives.
• Perform other related duties.
• Ph.D. in Biological Science or related field
• Three years' experience
• Highly Preferred Experience:
• Extensive experience working with mouse models, including performing stereotaxic injections.
• Strong background in molecular and cell biology.
• Experience with laboratory techniques, including cell culture, DNA/RNA isolation, cellular fractionation, Western blotting, PCR/qRT-PCR, in situ hybridization, and immunohistochemical labeling.
• Strong interest in neurodegeneration highly preferred.
• Demonstrated self-motivation, enthusiasm, and scientific rigor.
• Ability to work independently at the bench.

Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.