Job Description

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

The Commercial Ops & Analytics Manager will play a critical role in establishing and driving commercial excellence across the UK organization. This position is responsible for optimizing sales force strategy, performance, and execution through data-driven insights, advanced analytics, incentive compensation design, and field effectiveness initiatives.

The role partners closely with UK Head of Commercial and their sales leadership, Marketing, Medical, Finance, and Global & regional commercial teams to ensure the UK field organization is aligned, productive, and prepared to achieve launch and growth objectives.

Key Responsibilities

Sales Force Strategy & Optimization

• Advise and support sales force sizing, structure, and territory alignment in line with business objectives and market dynamics
• Develop and maintain call planning, targeting, and segmentation strategies in collaboration with UK Head of Commercial and sales leadership
• Continuously assess field deployment effectiveness and recommend improvements

Performance Analytics & Reporting

• Design and deliver dashboards, KPIs, and performance reports for UK leadership
• Analyze sales results, field activity, and promotional effectiveness to generate actionable insights
• Support forecasting, trend analysis, and scenario planning and market research analysis (in collaboration with marketing)

Incentive Compensation

• Lead the design, implementation, and administration of incentive compensation plans for review and approval by UK leadership
• Ensure alignment of incentives with strategic priorities and compliance requirements
• Partner with Finance and HR on goal setting, payout calculations, and plan communication

Field Effectiveness & Execution

• Drive initiatives to improve sales force productivity, capability, and execution quality
• Support CRM optimization adoption and use for clear business benefit (e.g., Veeva CRM) and optimal customer experience
• Collaborate with sales management to identify performance gaps and learning opportunities

Cross-Functional Collaboration

• Act as a trusted thought partner to UK Leadership and Commercial, Medical and Access stakeholders
• Align local SFE initiatives with any Regional or Global Commercial Excellence standards
• Support all launch readiness and post-launch optimization activities cross functionally as needed

Qualifications & Experience

Required

• Bachelor’s /Master degree in Business, Life Sciences, Analytics, or a related field such as Finance
• 8+ years of experience in Sales Force Effectiveness, Commercial Excellence, or Analytics within the pharmaceutical or biotech industry
• Strong expertise in incentive compensation, field analytics, and CRM systems
• Proven ability to translate data into strategic recommendations
• Experience working cross-functionally in a matrix organization
• Fluent in English

• Launch experience in specialty or rare disease markets
• Experience working with global or regional commercial teams
• Strong knowledge of the UK pharmaceutical market and compliance environment

Key Competencies

• Strategic and analytical mindset
• High attention to detail and operational excellence
• Strong stakeholder management and communication skills
• Ability to influence without authority
• Hands-on, proactive, and solution-oriented approach

We are committed to fostering an inclusive and diverse workplace and do not discriminate on the basis of any legally protected characteristics. Madrigal processes your personal data in connection with its recruitment and talent sourcing activities in accordance with applicable data protection laws. Further information about how your personal data is processed, together with details of your rights and how to exercise them, is available in our Job Applicant Privacy Notice, which is made available to you if you apply through Workday.

Please note that this job description is not exhaustive and may evolve over time. Only shortlisted candidates will be contacted. Applicants must be authorized to work in the country of employment at the time of application. Employment terms, where applicable, will be governed by relevant collective bargaining agreements.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.