Job Description

ROLE SUMMARY:

Drives the practical application of large language models (LLMs) and agentic artificial intelligence (AI) across the Inflammation & Immunology (I&I) portfolio by partnering closely with clinical and scientific teams to identify high-value use cases, building reusable workflows, and ensure adoption, rigor, and impact. This role sits within AI Delivery & Enablement (AIDE), the Systems Immunology line created to make AI and omics workflows practical across I&I through the conversion of repeat asks into reusable capabilities embedded in day-to-day scientific work.

The role sits at the intersection of clinical sciences and applied AI. The strongest candidate will have the clinical development experience to recognize where work can accelerate - study design, feasibility, trial conduct, clinical data review, and regulatory readiness – and clinic-omics fluency to connect those workflows to biomarker strategy, endpoint development, patient stratification, and high-dimensional data from clinical and translational studies. Near-term, the emphasis is clinical execution, where repetitive, document- and data-heavy work offers the fastest gains. Over time, the greater differentiation will come from extending those workflows into clinical omics analysis. The ideal candidate can operate across both domains, while bringing clear depth in at least one. Above all, this is a hands-on practitioner role focused on building and applying reusable AI workflows, not an AI governance or program-management role.

ROLE RESPONSIBILITIES:

• Identify high-value, repeat use cases across I&I clinical development and translational science where LLMs, agentic AI, and workflow automation can materially improve the speed, quality, and accessibility of the work; then design, build, and refine the reusable AI tools that address them.
• Work directly with clinical scientists, clinical operations, biostatistics, translational teams, and computational biologists to understand real workflow pain points, define fit-for-purpose solutions, and iterate quickly toward tools that are scientifically useful and operationally adopted.
• Work across the Digital ecosystem to prevent duplication and deploy existing platforms where appropriate, bringing the scientific requirements and evaluation criteria that make build-or-buy decisions defensible.
• Apply the same rigor to AI that you would to any clinical or scientific method: fit-for-purpose evaluation, grounded outputs, documentation, guardrails, disclosure of model limitations, and human oversight where it matters, with particular care where workflows touch GCP-governed or otherwise regulated data.
• In the near term, concentrate on clinical execution, where study design, feasibility, data review, and submission readiness offer the fastest and most visible gains; over time, extend the same approach to clinical omics and translational data, where the capability is harder to build and holds its value longer.
• Throughout, raise AI fluency among collaborators by demonstrating practical workflows, explaining trade-offs clearly, and helping scientists build confidence in the responsible use of LLM-enabled tools.

BASIC QUALIFICATIONS:

• PhD with 1+ years of experience OR Master’s degree and 5+ years of experience, OR Bachelor’s degree and 6+ years of experience. Advanced degree in a clinical, life-science, computational-biology, or related quantitative field preferred.
• Direct experience supporting clinical development, clinical science, clinical operations, clinical data review, or regulatory science, with a strong working understanding of GCP, clinical trial conduct, and the drug development process.
• Experience with omics or other high-dimensional data from clinical or translational studies - biomarker and endpoint work, patient stratification, or exploratory and mechanistic analysis - and with translating those results into development decisions.
• Depth in both clinical execution and clinical omics is ideal; genuine depth in one with credible working knowledge of the other is acceptable.
• Recent, hands-on experience applying LLMs, agentic AI, or workflow automation in your own scientific work. For example, agent skill or instruction files you wrote, agents or assistants you stood up on an enterprise AI platform, retrieval workflows you configured, or analyses you ran with AI in the loop. Oversight of AI work done by others does not substitute; building or training models is not required.
• Demonstrated ability to build practical, reusable workflows rather than one-off analyses.
• Experience working directly with domain users to translate ambiguous needs into useful solutions, with strong collaboration and communication skills, and the ability to influence without formal authority.
• Sound judgment regarding methodological rigor, model limitations, evaluation, and the appropriate role of human oversight in AI-enabled clinical and scientific workflows.

PREFERRED QUALIFICATIONS:

• Coding experience, Python or similar, sufficient to prototype, automate, and read what engineers build.
• Clinical scientist with hands-on experience in deploying AI, not just clinical exposure.
• Experience in immunology and inflammation (I&I) or an adjacent therapeutic area.
• Experience with single-cell, spatial, proteomic, or other high-dimensional platforms applied to clinical samples.
• Familiarity with scientific evidence synthesis, literature and document workflows, retrieval-augmented approaches, or multi-step workflows over structured and unstructured scientific information.
• Experience with agentic orchestration, prompt and program design, workflow automation, or multimodal AI systems.
• Familiarity with emerging regulatory expectations for AI in drug development; direct interaction with agencies such as the FDA or EMA, or contribution to submissions.
• Experience deploying AI in regulated environments, and with external technology partners, vendors, or academic collaborators.
• Strong publication or open-source record.

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

Additional Job Details:

• Last date to apply is September 16, 2026
• Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.

The annual base salary for this position ranges from $139,100.00 to $231,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.

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