
Award-winning and bold innovation. Modern Tech-Stack.Impactingthe future.
Technical Lead - Artificial Intelligence
£70,000 - £77,000plusbenefits
Reports to:Head of Engineering
Grade:P3 (MP)
DirectorateChief Operating Office
Contract2 year fixed-term contract
Hours:Full time 35 hours per week
Location:Stratford, London, high flexibility
We knowgreat workdoesn’thappen in just one place or one way. This role is designed to be highly flexible, with the opportunity to worklargely remotely, alongside occasional time in our offices for collaboration when it adds the most value.
Visa sponsorship:You must be eligible to work in the UK to apply for this vacancy. Cancer Research UKis notable tooffer visa sponsorship.
Closing date: 31 May2026, 23:55 Note we are shortlisting onan ongoing basis – please do not delay applying for the role.
How do I apply?
Weoperatean anonymised shortlisting process in our commitment to equality, diversity, and inclusion. CVs arerequiredfor all applications; but wewon’tbe able to view them until we invite you for an interview. Instead, we ask you to fully complete theapplication questions andwork history section of the online application form for us to be able to assess you quickly, fairly, and objectively.
If you require more time to apply as part of a reasonable adjustment, please contact recruitment@cancer.org.uk as soon as possible.
Recruitment process: 3stage interview processconsisting ofa screening call,role-basedcompetencyinterviewandtechnical task.
At Cancer Research UK, we exist to beat cancer.
At Cancer Research UK, we are a community of professionals with purpose. Every day, we push boundaries to beat cancer—yet we know we must go
Technical Lead – Artificial Intelligence
At Cancer Research UK,we’reharnessing the power of Artificial Intelligence to help beat cancer. From Generative and Agentic AI to machine learning, AI is becoming a transformative capability across our organisation – helping us work smarter, accelerate scientific discovery, and create more personalised and meaningful experiences for our supporters.
This is a chance to take on a highly flexible Technical Lead role where you can apply your deep technicalexpertiseto purposeful work, while enjoying the autonomy to worklargely remotelyand shape solutions that genuinely matter.
About the role
As a Technical Lead,you’llplay a critical role in turning ambitious AI opportunities intohigh‑quality, scalable technology solutions.You’llwork across the full lifecycle – fromearly‑stageideas and proof of concepts through toproduction‑readysystems that are embedded into the organisation.
You’llbe accountable for technical quality and delivery, working in a highly matrixed environment alongside internal product teams and trusted external partners.Technology‑agnosticand adaptable,you’llhelp shape problem statements, align solution designs to our AI vision, and guide teams through complex technical decisions.
This is ahands‑onleadership role that offers variety, influence, and the opportunity to help define how engineering practices evolve in the age of AI – all while supporting a mission that saves lives.
What will I be doing?
Act as Technical Lead for key AI initiatives atdifferent stages– from emerging ideas and proofs of concept through to solutions ready to scale and operationalise
Assess technical complexity, feasibility, and effort, helping teams make informed delivery decisions
Identifywhere foundational changes to platforms or infrastructure are needed to unlock AI capabilities
Work with Product Managers and colleagues to assess when and how to partner with external suppliers
Collaborate closely with Product and Project Managers, Architects, UX and Service Designers, and Business Analysts to understand user needs and iteratively design effective solutions
Provide technical assurance and constructive challenge for external technology partners
Validatehigh‑leveldesigns and support smooth transitions from design into delivery
Producelow‑leveldesigns, technical work plans, and documentation in line with delivery standards
Proactively surface technical risks, issues, and dependencies to initiative leads
Contribute significantly to testing strategies and plans to ensure solutions are robust, secure, and reliable
What are we looking for?
We’relooking for someone who brings both strong technical leadership and a genuine interest in how AI can createreal‑worldvalue.You’llhave:
Experience delivering CommercialOff‑the‑Shelf(COTS) andSoftware‑as‑a‑Service(SaaS) solutions, from procurement through to live operation
Recent,hands‑onexperience writing clean, maintainable, andwell‑testedcode using proven design patterns
The curiosity and adaptability to learn new languages, frameworks, and tools
Deep technicalexpertiseand the confidence to tackle complex problems independently
A strong interest in AI and innovation, with the ability torole‑modelhow modern engineering practices can evolve to deliver greater impact
Experience working across a range of domains, with the ability tocontext‑switchas priorities change
Proven experience running critical services in production and designing scalable, secure, andhighly availablesystems
Experience acting as a technical lead: defining solutions from scratch, shaping technical direction, and reviewing the work of other engineers
Knowledge of modern software delivery approaches (e.g. Scrum, Kanban), with some understanding ofspec‑drivendevelopment
Excellent communication skills, enabling you to explain complex ideas clearly and influence both technical andnon‑technicalstakeholders
Comfort working in complex environments with multiple priorities,and the resilience to adapt to continual change
Highly desirableto haveexperienceimplementing bespoke data, machine learning or AI solutions from pilot through to operationalisation.
Ideally hold a professional certification (e.g. cloud architect) in at least one major cloud data platform (e.g. GCP, Azure, AWS, Snowflake, Databricks) and will, ideally, be an active participant in that cloud’s community.
Our organisation values are designed to guide all that we do.
Bold: Act with ambition,courageand determination
Credible: Act with rigour and professionalism
Human:Act to have a positive impact on people
Together: Act inclusively and collaboratively
We’relooking for people who can believe in and embody these organisation values and can use them to drive forward progress against our mission to beat cancer.
You’ll help make breakthroughs possible—not just in laboratories, but in parliaments,communitiesand homes across the UK.
Together,we’rebuilding a future where everybody lives longer, better lives free from the fear of cancer.
Ready to use your voice to help save lives?We’dlove to hear from you.
What will I gain?
We create a working environment that supports your wellbeing and provide a generous benefits package, a wide range of career and personal development opportunities and high-quality tools. Our policies and processes enable you to improve your work-life balance, take positive steps in your career and achieve your personal wellbeing goals.
You can explore our benefits by visitingourcareers web page
Internal applicants' eligibility criteria
Internal candidates should ideally have completed their 6-month ‘getting started’ period before applying for other roles. You should also advise your current line manager at the point you make an internal application, or at the latest, at the point of being invited for an interview.
All internal candidates applying for a secondment, must have:
completed their getting started period
discussed their intention to apply and gained approval to apply with their line manager
been in their substantive (home) role for at least 6 months (this is only applicable if you have previously been on secondment)
If you do not confirm that you meet these requirements, we will not be able to progress your application.
Additionalinformation
For more information about working with usplease visit our websiteor contact us at recruitment@cancer.org.uk
For more updates on our work and careers, follow us on: LinkedIn, Facebook, Instagram, Xand YouTube
Our vision is to create a charity where everyone feels like they belong, benefits from and participates in, the work we do. We actively encourage applications from people of all backgrounds and cultures, in particular those from ethnic minority backgrounds who are currently under-represented.
We want to see every candidate performing at their best throughout the job application process, interview process and whilst at work. We therefore ask you to inform us of any concerns you have or any adjustments you might need to enable this to happen. Please contact recruitment@cancer.org.uk or 020 3469 8400 as soon as possible.
Unfortunately, we are unable to recruit anyone below the age of 18, so that we can protect young people from health & safety and safeguarding risks.

Cancer Research UK is the world's leading cancer charity dedicated to saving lives through research, influence and information. Nearly one in two of us will get cancer in our lifetime, but we’re finding new ways to outsmart it, so that more people can live longer, better lives free from the fear of cancer.
We carry out scientific research to help prevent, diagnose and treat cancer and our groundbreaking work, funded almost entirely by the general public, will ensure that millions more people survive.
Together we are beating cancer.
Registered charity No. 1089464.