Job Description

The Position

Genentech, Inc. seeks a Scientist 3 at its South San Francisco, California location.

Duties: Initiate, direct, and execute pre-clinical scientific research and development strategies for oncology drug discovery. Identify, validate, and mechanistically characterize novel oncology targets. Investigate the feasibility of new scientific principles by leveraging a broad range of innovative technologies, including in vivo, in vitro, and ex vivo model systems, as well as functional approaches like mass-spectrometry and CRISPR. Perform various biochemical, molecular biology, and cell-based assays, such as western blotting, cell-line engineering, and proliferation assays with organoids. Maintain up-to-date knowledge of scientific literature, publish findings in peer-reviewed journals, and present work at conferences. Advise management on corporate research and development, contribute to patent applications, and collaborate with diverse teams across the organization.

Education and Experience Requirement: Bachelor’s degree, or foreign degree equivalent, in Biochemistry, Cell & Molecular Biology, Biophysics or a closely related field and 2 years of industry experience in the job offered or a closely related position.

Specials Skills Requirement: Employer requires 2 years of experience with each of the following: •Cell-line engineering: lentiviral & CRISPR-based approaches including cloning strategies; •Molecular biology techniques: construct design & engineering; •Functional genomics: CRISPR & ORF overexpression; •Cell proliferation assays: conventional & advanced model systems including organoids; •Cell biological assays: immunofluorescence & high content imaging; •Biochemical techniques: western blotting, co-immunoprecipitation, and biochemical reconstitution.

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Worksite: 1 DNA Way, South San Francisco California, 94080. The expected annual salary range for this position based on the primary location for this position of South San Francisco, California is $147,864 to $192,000 per year. Actual pay within the range will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at (https://roche.ehr.com/default.ashx-CLASSNAME=splash)

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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